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Research
Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective mannerChemotherapy is included in treatment regimens for many solid cancers, but when administered as a single agent it is rarely curative. The addition of immune checkpoint therapy to standard chemotherapy regimens has improved response rates and increased survival in some cancers. However, most patients do not respond to treatment and immune checkpoint therapy can cause severe side effects. Therefore, there is a need for alternative immunomodulatory drugs that enhance chemotherapy.
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Post-surgery financial toxicity and its influencing factors in colorectal cancer care: A cross-sectional studyThis study aimed to investigate the influence factors of financial toxicity experienced by colorectal cancer patients after surgery. The results will provide deep insights for developing effective intervention strategies to address this common issue of colorectal cancer care.
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Impacts of armed conflicts on tuberculosis burden and treatment outcomes: a systematic reviewThis systematic review aimed to summarise existing literature on the impacts of armed conflicts on tuberculosis burden and treatment outcomes.
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Clinician perceptions of research priorities for the management of noncritically ill patients admitted to hospital with SARS-CoV-2 infectionThe changing phenotype of coronarvirus disease 2019 (COVID-19) may quickly render guideline-recommended interventions obsolete. We developed a 40-question clinician survey in consultation with the Australasian COVID-19 Trial site investigators. The survey was designed to assess clinician perceptions of the current treatment strategies and future research priorities in the management of non-critically ill patients admitted to hospital with SARS-CoV-2 infection.
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Interobserver Agreement When Diagnosing Hypoventilation in Children With Neuromuscular DisordersNeuromuscular disorders can lead to nocturnal hypoventilation. Accurate diagnosis of hypoventilation is imperative to guide treatment decisions. This study determined interobserver agreement for a number of definitions of nocturnal hypoventilation in children and adolescents with neuromuscular disorders.
News & Events
Urgent action needed to tackle health impacts of climate changeThe Kids Research Institute Australia supports calls from the Intergovernmental Panel on Climate Change (IPCC) for transformational action if we are to secure a liveable future.
Research
Amped Out: An Energy Drink StudyThe Kids Research Institute Australia is conducting a research study to evaluate a 4-month trial ban on the sale of energy drinks to children in all retail stores in Bridgetown.
News & Events
How the pandemic has shaped the mental health of our kidsThe Kids Research Institute Australia researchers went into 79 WA primary and secondary schools in 2020.
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The Life Course CentreThe Australian Research Council (ARC) Centre of Excellence for Children and Families Over the Life Course
Research
The ARC Centre of Excellence for Children and Families over the Life Course (Life Course Centre or LCC)The Life Course Centre is a national centre funded by the Australian Research Council Centre of Excellence Scheme and hosted through the University of Queensland with collaborating nodes at the University of Western Australia, Sydney University and University of Melbourne.