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Research

The oral microbiome of breastfed infants is distinct from that of formula-fed infants. However, breastfeeding characteristics, such as time spent breastfeeding (min/24 h), breastfeeding frequency (number of breastfeeds per day), and human milk intake (ml/day) vary significantly between breastfeeding dyads.

Research

Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is an ultrarare genetic condition causing developmental epileptic encephalopathy characterized by seizures and motor and intellectual disabilities. No disease-modifying therapies are available, and treatments focus mainly on symptom management to improve quality of life.

Research

Despite recent improvements in treatment modalities for cystic fibrosis (CF), there is currently limited evidence and a lack of consensus regarding optimal treatment strategies for the different aspects of CF, including pulmonary exacerbations (PEx). We aimed to establish a prospective cohort of people with CF (pwCF) to evaluate alternative approaches to managing CF in the era of modulator therapies.

Research

OLIG2-expressing tumor stem cells have been shown to drive recurrence in Sonic Hedgehog (SHH)-subgroup medulloblastoma (MB) and patients urgently need specific therapies to target this tumor cell population.

Research

Tick bites and tick-related diseases are on the rise. Diagnostic tests that identify well-characterised tick-borne pathogens (TBPs) possess limited capacity to address the causation of symptoms associated with poorly characterised tick-related illnesses, such as debilitating symptom complexes attributed to ticks (DSCATT) in Australia. Identification of local signals in tick-bitten skin that can be detected systemically in blood would have both clinical (diagnostic or prognostic) and research (mechanistic insight) utility, as a blood sample is more readily obtainable than tissue biopsies.

Research

High levels of sedentary behaviour are associated with poor child health outcomes such as obesity. Early childhood education and care (ECEC) services are a key intervention setting. Most ECEC policy-based interventions focus on children's nutrition and physical activity with few aimed at children's sedentary behaviour.

Research

Body position and movement during sleep is assessed for both clinical and research purposes. A diverse array of both assessment tools and classification systems are used to capture and code sleep biomechanics data.

Research

In Western Australia (WA) social activities occur in aquatic environments where alcohol promotion and consumption may be prevalent creating an aquatic alcogenic environment. This poses a challenge for drowning prevention efforts.

Research

Pseudomonas aeruginosa infections in the lungs affect millions of children and adults worldwide. To our knowledge, no clinically validated prognostic biomarkers for chronic pulmonary P. aeruginosa infections exist. Therefore, this study aims to identify potential prognostic markers for chronic P. aeruginosa biofilm lung infections.

Research

This study explores the incidence of preoperative hypophosphatemia and whether hypophosphatemia may have affected patient or trial outcomes for those who received ferric carboxymaltose

News & Events

Have you ever wondered how other parents manage their kids’ device use? As part of a survey for our Cyber Savvy Project, The Kids researchers asked a group of parents for their top tips regarding their child's use of devices.

News & Events

Mobile phones are an important part of diabetes management but its also important to set some family rules for your child's technology use.

We rely on the support of donors & fundraisers to be able to conduct the life changing pediatric research we do on a day-to-day basis. Will you help?

One of Australia’s leading cancer research centres continues to be powered by parents who decided to fight back. Hard.

News & Events

A brave young man stepped up to the plate on Friday to do his part in the battle against cancer.

Maddox Ball and The Kids researcher Dr Ingrid Laing might not look like they have a lot in common but they share a very special bond.

Many people would be daunted when tasked with coordinating, from scratch, a new The Kids Research Institute Australia satellite site to service WA’s north. But not John Jacky

News & Events

At The Kids Research Institute Australia, we’ve always known what a fantastic community we have around us.

News & Events

A ground-breaking global clinical trial to improve the lifelong lung health of children born extremely prematurely has been awarded a Medical Research Future Fund (MRFF) International Clinical Trials Collaborations Grant totalling almost $3 million.

Professor Jonathan Carapetis has made eliminating rheumatic heart disease his life’s work.