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Research

Enhancing functional recovery for young people recovering from first episode psychosis via sport-based life skills training: outcomes of a feasibility and pilot study

Early intervention within First Episode Psychosis (FEP) recovery efforts support functional recovery in several ways, including increasing levels of (1) physical activity (2) life skills, and (3) social connectivity. Sport has been proposed as an ideal platform to target these three goals simultaneously.

Research

Fetal alcohol spectrum disorder: Development of consensus referral criteria for specialist diagnostic assessment in Australia

The use of standard methods to identify when to refer individuals who may have FASD for specialist assessment could help improve the identification of this...

News & Events

Physical activity vital to diabetes management

Parents of children with Type 1 Diabetes often feel they need to wrap their child in cotton wool rather than let them get on with the job of being a kid and eve

News & Events

Jake jumps at trial opportunity

Meet Jake O’Brien, the first patient to take part in the longest and largest at-home trial of a hybrid closed-loop insulin pump.

Mental health and wellbeing

We are trying to understand what underlies mental health problems in young people with diabetes, with a school-related focus, and how we can best treat them.

News & Events

Covid Vaccination Statement

Re: Recommendations from the Diabetes and Endocrinology Department at Perth Children’s Hospital and the Children’s Diabetes Centre at The Kids Research Institute Australia regarding COVID-19 vaccination for children with diabetes

Research

Bringing optimised COVID-19 vaccine schedules to immunocompromised populations: statistical elements and design

Bringing optimised coronavirus disease 2019 (COVID-19) vaccine schedules to immunocompromised populations (BOOST-IC) is a multi-site, adaptive platform trial designed to assess the effect of different booster vaccination schedules in the Australian immunocompromised population on the immunogenicity, safety and cross-protection against COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants. 

Research

A digital intervention to support childhood cognition after the COVID-19 pandemic: a pilot trial

Difficulties in executive functioning (EF) can result in impulsivity, forgetfulness, and inattention. Children living in remote/regional communities are particularly at risk of impairment in these cognitive skills due to reduced educational engagement and poorer access to interventions. This vulnerability has been exacerbated by the COVID-19 pandemic and strategies are needed to mitigate long-term negative impacts on EF.

Research

The histone demethylase dLsd1 regulates organ size by silencing transposable elements

The specific role of chromatin modifying factors in the timely execution of transcriptional changes in gene expression to regulate organ size remains largely unknown. Here, we report that in Drosophila melanogaster depletion of the histone demethylase dLsd1 results in the reduction of wing size. dLsd1 depletion affects cell proliferation and causes an increase in DNA damage and cell death.

Research

Variation in excess all-cause mortality by age, sex, and province during the first wave of the COVID-19 pandemic in Italy

Although previous evidence suggests that the infection fatality rate from COVID-19 varies by age and sex, and that transmission intensity varies geographically within countries, no study has yet explored the age-sex-space distribution of excess mortality associated with the COVID pandemic.