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Dissecting the regulation of bile-induced biofilm formation in Staphylococcus aureus

Dissecting the regulation of bile-induced biofilm formation in Staphylococcus aureus. Aspiration of bile into the cystic fibrosis (CF) lung has

Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children

Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children

The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials

The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials

Community Involvement

As part of our research development and planning we invite members of the community to work with us. Click here to find out how.

The potential of antisense oligonucleotide therapies for inherited childhood lung diseases

The potential of antisense oligonucleotide therapies for inherited childhood lung diseases Antisense oligonucleotides (AOs) are an emerging

News & Events

Lung health of Aboriginal children hospitalised with chest infections improved following co-designed intervention

A co-designed and culturally secure intervention to improve medical follow-up for Aboriginal children hospitalised with acute chest infections resulted in higher follow-up rates and improved longer-term lung health outcomes for children.

News & Events

Wal-yan Centre scholarship awardees to research interventions for improving lung health

As part of the Wal-yan Respiratory Research Centre’s aim to support the next generation of scientists in children’s respiratory research, a competitive scholarship program was introduced this year.

News & Events

Discovery Centre lightens the load for hospital families

The opening of the Discovery Centre has made trips to Perth Children's Hospital much more enjoyable for mum Alianna Celisano and her three boys.

Research

Early childhood development strategy for the world's children with disabilities

Early childhood is foundational for optimal and inclusive lifelong learning, health and well-being. Young children with disabilities face substantial risks of sub-optimal early childhood development, requiring targeted support to ensure equitable access to lifelong learning opportunities, especially in low- and middle-income countries. 

Research

Effects of ganaxolone on non-seizure outcomes in CDKL5 Deficiency Disorder: Double-blind placebo-controlled randomized trial

CDKL5 deficiency disorder (CDD) is a rare developmental and epileptic encephalopathy. Ganaxolone, a neuroactive steroid, reduces the frequency of major motor seizures in children with CDD. This analysis explored the effect of ganaxolone on non-seizure outcomes.