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Research

The complement system in systemic lupus erythematosus: An update

The complement system plays a major role in the autoimmune disease, systemic lupus erythematosus (SLE). This review highlights the many roles of complement for

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Diversity of Nontypeable Haemophilus influenzae strains colonizing Australian Aboriginal and non-Aboriginal children

Nontypeable Haemophilus influenzae (NTHI) strains are responsible for respiratory-related infections which cause a significant burden of disease in...

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Deregulated expression of connective tissue growth factor is linked to poor outcome in human cancer

Connective tissue growth factor (CTGF/CCN2) has long been associated with human cancers. The role it plays in these neoplasms is diverse and tumour specific.

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Teacher–Child Relationship, Parenting, and Growth in Likelihood and Severity of Physical Aggression in the Early School Years

This study investigated the likelihood of children showing problems with parent-rated physical aggression, and on the severity of problems, for 374 children.

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Impact of assisted reproductive technologies on intrauterine growth and birth defects in singletons

This paper presents data that infants born following assisted reproductive technologies (ART) compared with non-ART singletons display increases in low birth...

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Parental occupational pesticide exposure and the risk of childhood leukemia in the offspring: Findings from the childhood leukemia international consortium

Maternal occupational pesticide exposure during pregnancy and/or paternal occupational pesticide exposure around conception have been suggested to increase...

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Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults.

The aim of this study was to evaluate the associations between bone mass in young adults and three body composition measurements: lean body mass, fat mass...

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Measuring exposure to solar ultraviolet radiation using a dosimetric technique: Understanding participant compliance issues

We investigated the types and determinants of noncompliance associated with a protocol for use of polysulphone UVR dosimeters.

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Preeclampsia and cardiovascular disease share genetic risk factors on chromosome 2q22

This study aimed to further evaluate the pleiotropic effects of these preeclampsia risk variants in an independent Australian population-based cohort.

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Invasive Staphylococcus aureus Infections in Children in Tropical Northern Australia

We conducted a retrospective review for all cases of S aureus bacteremia and sterile site infections, for children under 15 years, in northern Australia over...

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Using Systems Theory to Understand and Respond to Family Influences on Children's Bullying Behavior

This article addresses Systems Theory as it applies to school-age children's bullying behavior.

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Birth outcomes and academic achievement in childhood: A population record linkage study

This study used population-based record linkage to examine the association between early life risk factors and academic achievement.

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Changes in the clinical and epidemiological features of group A streptococcal bacteraemia in Australia's northern territory

We aimed to measure the incidence and severity of invasive Group A Strep disease in the NT since 1996.

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Examining ERBB2 as a candidate gene for susceptibility to leprosy (Hansen's disease) in Brazil

This study examines whether polymorphisms in the ERBB2 gene were associated with leprosy in primary and replication cohorts from northeastern Brazil.

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Childhood and parental diagnostic radiological procedures and risk of childhood brain tumors

We found no evidence of positive associations between risk of childhood brain tumours overall and childhood or parental pre-pregnancy radiological procedures.

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Advancing the management and control of typhoid fever: a review of the historical role of human challenge studies

Improved understanding of Salmonella Typhi infection can help accelerate the development of improved vaccines and diagnostic tests necessary for disease control

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Dendritic cells and multiple sclerosis: Disease, tolerance and therapy

Multiple sclerosis (MS) is a devastating neurological disease that predominantly affects young adults resulting in severe personal and economic impact.

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Diverging Trends in Gastroenteritis Hospitalizations during Two Decades in Western Australian Aboriginal and Non-Aboriginal Children

Our findings highlight the need to consider age, ethnicity, seasonality and climate when evaluating rotavirus vaccine programs.