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In utero exposure to low dose arsenic via drinking water impairs early life lung mechanics in miceAll alterations to lung mechanics following in utero arsenic exposure were recovered by adulthood.
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Hospitalisation rates for children with intellectual disability or autism born in Western Australia 1983-1999: A population-based cohort studyID and/or ASD were found to be associated with an increased risk of hospitalisation compared with the remainder of the population.
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Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrowInjection of BM-differentiated DCs from nonchimeric mice restored the reduced immune responses of PGE2-chimeric mice.
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Eating disorder symptom trajectories in adolescenceAdolescence is a period of developmental risk for eating disorders and eating disorder symptoms.
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Parental smoking and risk of childhood brain tumorsChildhood brain tumors (CBT) are the leading cause of cancer death in children, yet their etiology remains largely unknown.
News & Events
Funding boost to improve anaesthesia safety for kids with asthmaTelethon Kids Institute and the PMH Anaesthesia Research Team will work to improve the safety for young children with asthma undergoing general anaesthesia.
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Approaches to study the lifelong trajectories of children with neurodevelopmental conditionsWe argue that population-based studies are critical to overcome the selection bias seen in many clinical samples and to identify true variability within a...
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Neurocognitive functioning in adolescents with eating disorders: A population-based studyNeurocognitive deficits have been identified in eating disorders, including anorexia nervosa and bulimia nervosa.
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Women’s Views of their Maternity Services ExperienceThe following sections of this report result from a project undertaken to develop a theoretically-framed survey tool for use in monitoring and evaluating...
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Transforming growth factor-Beta in milkFindings suggest that TGF-Beta in milk may influence the development of immunological outcomes in offspring.
News & Events
Video: Aboriginal AsthmaWadjuk Nyungar man Walter McGuire talks about the importance of air quality to our health.
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Setting the RECORD straight: Developing a guideline for the reporting of studies conducted using observational routinely collected dataThere has been a dramatic increase in the availability of "routine data" for research purposes, including data from electronic medical records,...
News & Events
Research reveals new link between Vitamin D, lung bacteria and asthmaA The Kids for Child Health Research study has uncovered a new link between vitamin D levels and asthma.
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Multi-centre, multi-disciplinary study using a systems biology approach to investigate immunomodulation in children with acute wheezeIngrid Pat Laing Holt BSc PhD PhD, DSc, FRCPath, FRCPI, FAA Head, Children's Respiratory Science Emeritus Honorary Researcher 6319 1828 Ingrid.laing@
Research
Symptomatic viral infection is associated with impaired response to treatment in children with acute asthmaThe objective of this study was to examine the influence of viral respiratory infection (VRI) on treatment response in acute asthma in children.
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Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specificChronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear
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Bronchial brushings for investigating airway inflammation and remodellingAsthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable...
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Neonatal immune function and inflammatory illnesses in later life: lessons to be learnt from the developing world?With the emergence of allergic and autoimmune diseases in populations that have started to transit to a western lifestyle, there has been an increasing...
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House dust mite allergens in asthma and allergyIgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against
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Early immunological influences on asthma development: opportunities for early interventionEarly immunological influences on asthma development: opportunities for early intervention