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Research

Feasibility Testing and Refinement of a Supportive Educational Intervention for Carers of Patients with High-Grade Glioma — a Pilot Study

The aim of this pilot study was to test the feasibility and acceptability of a family carer intervention for carers of patients with high-grade glioma

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Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

Epigenetic changes at the GFI1 were linked to smoking exposure in-utero/in-adulthood and robustly associated with cardio-metabolic risk factors

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Diagnosis of Autism Spectrum Disorder According to Maternal-Race Ethnicity and Country of Birth: A Register-Based Study

An increased prevalence of autism spectrum disorder (ASD) among children of immigrant backgrounds has been observed

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Longitudinal effects of caregiving on parental well-being: the example of Rett syndrome, a severe neurological disorder

Our findings suggest that some opportunities do exist for clinicians to help optimise parental well-being

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Direct infant UV light exposure is associated with eczema and immune development

This study is the first to demonstrate an association between greater direct UV light exposures in early infancy with lower incidence of eczema

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Association between psychotic experiences and non-accidental self-injury: results from a nationally representative survey of adolescents

Adolescents reporting any sychotic experiences in the past 12 months reported increased likelihood of non-accidental self-injury in the same time period

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Key paediatric messages from the 2018 European Respiratory Society International Congress

Group Chairs and early career members highlight some of the most interesting findings in the field of paediatrics presented at the 2018 international ERS Congress

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Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis

These findings indicate that early CF lung disease is characterized by an increased mucus burden and inflammatory markers without infection or structural lung disease

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Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

We find that DNA methylation in neonatal blood is associated with birthweight, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation