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Changes in thymic regulatory T-cell maturation from birth to puberty: Differences in atopic childrenWe report vaccine efficacy against CIN3+ and adenocarcinoma in situ (AIS) in the end-of-study analysis of PATRICIA (PApilloma TRIal against Cancer In young...
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Early diet quality in a longitudinal study of Australian children: Associations with nutrition and body mass index later in childhood and adolescenceThe aims of this study were to determine whether early childhood dietary quality was associated with infant and adolescent nutrition, and body mass index.
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Genetic variants in novel pathways influence blood pressure and cardiovascular disease riskBlood pressure is a heritable trait influenced by several biological pathways and responsive to environmental...
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The dual-pathway and cognitive-behavioural models of binge eating: prospective evaluation and comparisonThe aim of this study was to evaluate and compare the dual-pathway, original cognitive-behavioural, and enhanced "transdiagnostic" cognitive-behavioural...
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Language, cognitive flexibility, and explicit false belief understanding: Longitudinal analysis in typical development and Specific Language ImpairmentThe hypothesis that language plays a role in theory-of-mind (ToM) development is supported by a number of lines of evidence.
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Significant Association between Common Polymorphisms in the Aromatase Gene CYP19A1 and Bone Mineral Density in Postmenopausal Women17β-Estradiol is important in maintaining bone structure, and regulation of its synthesis plays an important role in the development of postmenopausal...
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Development of an International Database for a Rare Genetic Disorder: The MECP2 Duplication Database (MDBase)The natural history of MECP2 duplication syndrome (MDS), a rare X-linked neurodevelopmental disorder with an estimated birth prevalence of 1/150,000 live births, is poorly understood due to a lack of clinical data collected for research. Such information is critical to the understanding of disease progression, therapeutic endpoints and outcome measures for clinical trials, as well as the development of therapies and orphan products.
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In vitro antibacterial activity of Western Australian honeys, and manuka honey, against bacteria implicated in impetigoImpetigo is a contagious skin disease caused by Staphylococcus aureus and Streptococcus pyogenes. Without treatment, impetigo may be recurrent, develop into severe disease, or have serious, life-threatening sequelae. Standard treatment consists of topical or systemic antibiotic therapy (depending on severity), however, due to antibiotic resistance some therapies are increasingly ineffective.
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Unusual 2020 respiratory syncytial virus bronchiolitis season in Western Australia: Not explained by weatherTo describe and explore the relationship between weather and the unusual 2020 bronchiolitis season in Western Australia during the COVID-19 pandemic.
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Non-severe burn injury increases cancer incidence in mice and has long-term impacts on the activation and function of T cellsRecent evidence suggests that burn patients are at increased risk of hospital admission for infection, mental health conditions, cardiovascular disease and cancer for many years after discharge for the burn injury itself.