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Research
Benchmarking Imputed Low Coverage Genomes in a Human Population Genetics ContextOngoing advances in population genomic methodologies have recently enabled the study of millions of loci across hundreds of genomes at a relatively low cost, by leveraging a combination of low-coverage shotgun sequencing and innovative genotype imputation methods. This approach has the potential to provide abundant genotype information at low costs comparable to another widely used cost-effective genotyping approach-that is, SNP panels-while avoiding potential issues related to loci being ascertained in distantly related populations.
Research
Rewiring endogenous genes in CAR T cells for tumour-restricted payload deliveryThe efficacy of chimeric antigen receptor (CAR) T cell therapy in solid tumours is limited by immunosuppression and antigen heterogeneity. To overcome these barriers, 'armoured' CAR T cells, which secrete proinflammatory cytokines, have been developed. However, their clinical application has been limited because of toxicity related to peripheral expression of the armouring transgene.
Research
The usability and feasibility of a self-compassion chatbot (COMPASS) for youth living with type 1 diabetesAlthough it is well established that youth with type 1 Diabetes (T1D) experience high rates of distress, current clinical care is often under-resourced and unable to provide sufficient or timely psychological support. The current study was designed to evaluate the safety, usability and feasibility of 'COMPASS,' a self-compassion chatbot intervention.
Time to reflect After your leadership team has completed an activity it is important to take time to reflect on how it went and things you may have
Cybersafe practices are precautions we can take to make sure our interactions online are safe and positive. Download the "My Online Status" in the
The Health Promotion and Education Research Team at The Kids Research Institute Australia received funding from the auDA Foundation to develop this
The END RHD CRE focuses priority research projects that will help achieve the singular target of producing the Endgame Strategy.
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Carol's story: losing a parent to RHDAfter being diagnosed with rheumatic heart disease at ten, Elizabeth had to leave country and her family for a large chunk of her childhood so she could be treated in Adelaide.
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