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Research

Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia

The aim of our study was to investigate whether CBL0137 has potential as a therapeutic and chemopotentiating compound in MLL-r leukemia

Research

Sensitizing the Tumor Microenvironment to Immune Checkpoint Therapy

In this review we explore the current literature about the predictive characteristics of the tumor microenvironment and discuss therapeutic approaches

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Prevalence and outcomes of young people with concurrent autism spectrum disorder and first episode of psychosis

Individuals with concurrent first episode of psychosis and ASD can present with distinct clinical characteristics that require specialised assessment and treatment

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Characterisation of peripheral bone mineral density in youth at risk of secondary osteoporosis - A preliminary insight

Neuromuscular disorders, chronic diseases and low motor competence have a strong correlation to bone health for appendicular bone parameters in youth

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Burden of skin disease in two remote primary healthcare centres in northern and central Australia

Skin infections are an under-appreciated and dominant reason for presentation to primary healthcare centres in these indigenous communities

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Transcriptional blood signatures for active and amphotericin B treated visceral leishmaniasis in India

Amphotericin B provides improved therapy for visceral leishmaniasis (VL) caused by Leishmania donovani

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Recurrence Risk of Autism in Siblings and Cousins: A Multinational, Population-Based Study

The present estimates of relative recurrence risks for autism spectrum disorder and childhood autism will assist clinicians and families in understanding autism risk

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Incidence and prevalence of falls in adults with intellectual disability living in the community: a systematic review

Synthesized findings demonstrate that people with intellectual disability, who live in community or residential settings, may fall more frequently, and at a younger age

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The Global Lung Function Initiative (GLI) Network ERS Clinical Research Collaboration: how international collaboration can shape clinical practice

The Global Lung Function Initiative is working to improve the interpretation of lung function: an update on current work and the opportunities for further engagement

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Serotonin and aggressive behaviour in children and adolescents: a systematic review

Findings were mixed, with support both for negative and for positive associations of central nervous 5-HT function with aggression in children and adolescents