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Research
Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.We propose that this system provides a model for the differentiation and adaptation of monocytes entering the intestinal lamina propria.
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Characteristics associated with clinical severity and inflammatory phenotype of naturally occurring virus-induced exacerbations of asthma in adultsType 2 inflammation is present in patients during virus-induced asthma exacerbations, to the same degree as non-viral exacerbations
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Pulmonary delivery of virosome-bound antigen enhances antigen-specific CD4+ T cell proliferation compared to liposome-bound or soluble antigenPulmonary administration of biomimetic nanoparticles loaded with antigen may represent an effective strategy to directly modulate adaptive immune responses
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Induced sputum to detect lung pathogens in young children with cystic fibrosiswe aimed to determine the sensitivity and specificity of induced sputum with and without airway clearance techniques to detect lower airway pathogens in kids.
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Prenatal omega-3 LCPUFA and symptoms of allergic disease and sensitization throughout early childhoodMaternal supplementation with 900 mg of ω-3 LCPUFA did not change the progression of IgE-mediated allergic disease symptoms or sensitization
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Topical antibiotics for chronic suppurative otitis mediaTo assess the effects of topical antibiotics for people with chronic suppurative otitis media.
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Aboriginal parent support: A partnership approachOur aim was to identify program elements, exploring participants’ perceptions of the program's suitability, feasibility, acceptability and effectiveness.
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The Ultra-High-Risk for psychosis groups: Evidence to maintain the status quoOur findings demonstrate that Ultra-High-Risk groups evidence a similar clinical risk profile when we expand this beyond transition to psychosis
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Aboriginal children and penicillin injections for rheumatic fever: How much of a problem is injection pain?We explore young Aboriginal people's and clinicians' experience of injection pain for the 10 years of penicillin injections young people are prescribed.
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“Arguments online, but in school we always act normal”: The embeddedness of early adolescent negative peer interactions within the whole of their offline and online peer interactionsOur aim was to study was to investigate how negative peer interactions on/offline are associated with each and with other daily interactions among adolescents.