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Research

Epigenetics of the non-coding RNA nc886 across blood, adipose tissue and skeletal muscle in offspring exposed to diabetes in pregnancy

Diabetes in pregnancy is associated with increased risk of long-term metabolic disease in the offspring, potentially mediated by in utero epigenetic variation. Previously, we identified multiple differentially methylated single CpG sites in offspring of women with gestational diabetes mellitus, but whether stretches of differentially methylated regions can also be identified in adolescent GDM offspring is unknown.

News & Events

Clinic news December 2021

Stay updated with the latest news and events from Clinikids in December 2021, focusing on child health innovations and community engagement. Explore more now!

RHYME study

Contact us If you'd like to get in touch, please contact us by phone or email. Phone: 0400 450 240 Email: rhyme@telethonkids.org.au Background The

News & Events

Congratulations Dr Anna Boggiss

Anna has been awarded a three-year Fellowship to tackle the urgent gap in care in young Western Australians living with type 1 diabetes who are at heightened risk of developing eating disorders.

News & Events

Aussies publish first RCT of hybrid closed loop systems

A world-first clinical trial has shown young people with type 1 diabetes have better glycaemic control and quality of life while on hybrid closed loop (HCL) systems versus conventional treatments, Australian endocrinologists say.

Report: Pathways of young people in contact with multiple government agencies in Western Australia

Findings of a research study examining the characteristics of service use by a cohort of young people born between 1994-1997 who used four government services.

Research

Linking the westernised oropharyngeal microbiome to the immune response in Chinese immigrants

Human microbiota plays a fundamental role in modulating the immune response. Western environment and lifestyle are envisaged to alter the human microbiota with a new microbiome profile established in Chinese immigrants, which fails to prime the immune system. Here, we investigated how differences in composition of oropharyngeal microbiome may contribute to patterns of interaction between the microbiome and immune system in Chinese immigrants living in Australia.

Research

Genome mining and characterisation of a novel transaminase with remote stereoselectivity

Here we report a novel ω-transaminase discovered in a marine sponge Pseudovibrio sp. isolate

Research

Predicting disease progression in cystic fibrosis

Comprehensive scores incorporating clinical, lung function, imaging and laboratory data will become essential in the future for predicting disease progression and for use in clinical trials