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Research

Key elements of Goal-Directed Training for children with cerebral palsy: A qualitative content analysis

Goal-directed training is an evidence-based occupational therapy intervention for children with cerebral palsy targeting motor performance and goal attainment. There is variability and limited description on goal-directed training delivery within the studies who found it a successful intervention. The aim of this study was to establish the who, what, why and how of goal directed training according to practicing occupational therapists.

Research

Gestational age as a predictor for subsequent preterm birth in New South Wales, Australia

There is no validated evidence base on predictive ability and absolute risk of preterm birth by gestational age of the previous pregnancy. We conducted a retrospective cohort study of mothers who gave birth to their first two children in New South Wales, 1994-2016. For each week of final gestational age of the first birth, we calculated relative and absolute risks of subsequent preterm birth.

Research

Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed Screens

The poor hit rates associated with conventional random peptide libraries present formidable challenges in genetic screening formats with limited throughput.

Research

Use of bevacizumab as a single agent or in adjunct with traditional chemotherapy regimens in children with unresectable or progressive low-grade glioma

Bevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity

Research

Multiomics and Systems Biology Are Needed to Unravel the Complex Origins of Chronic Disease

In this concept paper, we discuss multiomic approaches to studying immune dysregulation and highlight some of the challenges and opportunities

Research

Reconstructing the early global dynamics of under-ascertained COVID-19 cases and infections

Asymptomatic or subclinical SARS-CoV-2 infections are often unreported, which means that confirmed case counts may not accurately reflect underlying epidemic dynamics. Understanding the level of ascertainment (the ratio of confirmed symptomatic cases to the true number of symptomatic individuals) and undetected epidemic progression is crucial to informing COVID-19 response planning, including the introduction and relaxation of control measures.

Research

Asking QUestions about Alcohol in pregnancy (AQUA): A longitudinal cohort study of fetal effects of low to moderate alcohol exposure

Using detailed, prospective methods of data collection, the AQUA study will comprehensively examine the effects of low to moderate alcohol consumption...

Research

Lung function, airway inflammation, and polycyclic aromatic hydrocarbons exposure in mexican schoolchildren: A pilot study

To determine the association of exposure to polycyclic aromatic hydrocarbons (PAHs) with lung function and pH of exhaled breath condensate (EBC) in Mexican...

Research

Making a difference: Engaging both hearts and minds in research practice

This paper discusses the findings and the research process undertaken thus far for the Looking Forward Aboriginal Mental Health Project.