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Early detection of lung function abnormalities in young children with cystic fibrosisIn this review, we have examined the role of lung function testing in infants and preschool children with CF.
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Airway Epithelial Cells Condition Dendritic Cells to Express Multiple Immune Surveillance GenesAEC-conditioned DC showed selective upregulation of chemokines that recruit Th1 cells, but minimal change in chemokines linked to Th2 cell recruitment.
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MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63We hypothesized that reactivation of p53 by inhibition of its negative regulator will result in p53-mediated growth arrest and apoptosis.
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Tertiary paediatric refugee health clinic in Western Australia: Analysis of the first 1026 childrenThe aim of this study is to describe the epidemiology of common conditions in resettled paediatric refugees attending a tertiary multidisciplinary RHC.
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Peptides targeting the mitogen-activated protein kinase pathway (JNK/JUN) fail to reduce infarct volume after permanent MCAO in sprague dawley ratsIn this study we have assessed the ability of two TAT-fused peptides to reduce infarct volume and improve functional outcome following permanent ischaemia.
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Symptomatic viral infection is associated with impaired response to treatment in children with acute asthmaThe objective of this study was to examine the influence of viral respiratory infection (VRI) on treatment response in acute asthma in children.
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Changes in health professionals' knowledge, attitudes and practice following provision of educational resourcesWe provided health professionals in Western Australia (WA) with educational resources about prevention of prenatal alcohol exposure and fetal alcohol...
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Bronchial brushings for investigating airway inflammation and remodellingAsthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable...
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Evaluating the twin testosterone transfer hypothesis: A review of the empirical evidenceIn this paper we review the evidence that fetuses gestated with a male co-twin are masculinized in development, perhaps due to the influence of prenatal...
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Toll-like receptor 7 and 8 polymorphisms: associations with functional effects and cellular and antibody responses to measles virus and vaccineSuccessful defence against viral pathogens requires the rapid recognition of virus-specific "danger signals" and the activation of both innate and adaptive...