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Research

Single-cell transcriptomic and spatial landscapes of the developing human pancreas

Current differentiation protocols have not been successful in reproducibly generating fully functional human beta cells in vitro, partly due to incomplete understanding of human pancreas development. Here, we present detailed transcriptomic analysis of the various cell types of the developing human pancreas, including their spatial gene patterns. We integrated single-cell RNA sequencing with spatial transcriptomics at multiple developmental time points and revealed distinct temporal-spatial gene cascades.

Research

Rare disease education in Europe and beyond: time to act

People living with rare diseases (PLWRD) still face huge unmet needs, in part due to the fact that care systems are not sufficiently aligned with their needs and healthcare workforce (HWF) along their care pathways lacks competencies to efficiently tackle rare disease-specific challenges. Level of rare disease knowledge and awareness among the current and future HWF is insufficient.

Research

Evaluation of protocol amendments to the Environmental Determinants of Islet Autoimmunity (ENDIA) study during the COVID-19 pandemic

Liz Davis MBBS FRACP PhD Co-director of Children’s Diabetes Centre Co-director of Children’s Diabetes Centre Professor Davis is a paediatric

Research

Culturally competent communication in Indigenous disability assessment: a qualitative study

Indigenous people tend to exhibit a higher burden of disability than their non-Indigenous counterparts, and are often underserved by disability services. Engaging appropriately with Indigenous communities, families and individuals in the initial stages of disability assessment and planning is crucial in order to build trust and understanding of disability service models and ensure that Indigenous people receive support that is tailored to their needs and cultural realities. This article aims to identify key elements of culturally competent communication in Indigenous disability assessment and planning, and provide recommendations for strengthening capacity in this area.

Research

The Deep Genome Project.

The Deep Genome Project—to deliver the functional biological annotation of all human orthologous genomic elements in mice

Research

Wongi mi bardup (doing it our way): Methodologies promoting Aboriginal knowledges and cultural practices for Birthing on Noongar Boodjar

This paper sets out the methodological and theoretical considerations which framed how the Birthing on Noongar Boodjar project was conducted

Research Project Coordinator TETO Project

Research Project Coordinator, Health Promotion & Education Research

Allergies

Discover resources and science activities for kids for the topic 'Allergies'.

Research

Towards a Better Understanding of the Life Cycle of Trypanosoma copemani

To understand the biology and life cycle of Trypanosoma copemani, the growth requirements, and kinetics of infection of two new genotypes were investigated

Research

Hypersensitivity: Immunological

This comprehensive review provides an introduction to immunological hypersensitivity, discusses the sensitisation of T-cell lineages.