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Research

Expanding the clinical picture of the MECP2 Duplication syndrome

Perinatal characteristics, early childhood development and medical co-morbidities in MECP2 Duplication syndrome

Research

Screening for rheumatic heart disease: Quality and agreement of focused cardiac ultrasound by briefly trained health workers

After brief training, health workers with no prior experience in echocardiography can obtain adequate quality images and make a reliable assessment

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Systematic review and meta-analysis of respiratory viral coinfections in children

Coinfection is not associated with increased clinical severity, but further investigations by pathogen pairs are warranted

Research

25-hydroxyvitamin D status of pregnant women is associated with the use of antenatal vitamin supplements and ambient ultraviolet radiation

Vitamin D deficiency in a predominantly white Caucasian cohort of pregnant women is less prevalent than has been reported in other studies

Research

MACROD2 gene associated with autistic-like traits in a general population sample

The MACROD2 gene is a strong positional candidate risk factor for autistic-like traits in the general population

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Blood DNA methylation biomarkers predict clinical reactivity in food-sensitized infants

The diagnosis of food allergy (FA) can be challenging because approximately half of food-sensitized patients are asymptomatic.

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Cohort profile of the HealthNuts study: Population prevalence and environmental/genetic predictors of food allergy

HealthNuts is a single-centre, multi-wave, population-based longitudinal study designed to assess prevalence, determinants, natural history and allergy...

Research

TagDust2: A generic method to extract reads from sequencing data.

Arguably the most basic step in the analysis of next generation sequencing data (NGS) involves the extraction of mappable reads from the raw reads...

Research

Developing a Model to Account for Attrition Bias in a Longitudinal Cohort

Our objective was to develop a method that could be applied in a longitudinal cohort study to account for attrition bias in an investigation of exclusive...

Research

Big data in global health: Improving health in low- and middle-income countries

Over the last decade, a massive increase in data collection and analysis has occurred in many fields.