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Time to address the neglected burden of group A StreptococcusJonathan Jeffrey Carapetis AM Cannon AM MBBS FRACP FAFPHM PhD FAHMS BSc(Hons) BBus PhD Executive Director; Co-Head, Strep A Translation; Co-Founder
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Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 studyThe age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average.
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How many doses make a difference? An analysis of secondary prevention of rheumatic fever and rheumatic heart diseaseincreased adherence to penicillin prophylaxis is associated with reduced acute rheumatic fever recurrence and a likely reduction in mortality
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Scabies and risk of skin sores in remote Australian Aboriginal communities: A self-controlled case series studyThe association between scabies and skin sores is highly significant and indicates a causal relationship
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Group A Streptococcus, Acute Rheumatic Fever and Rheumatic Heart Disease: Epidemiology and Clinical ConsiderationsA directed approach to the differential diagnosis of acute rheumatic fever now includes the concept of low-risk versus medium-to-high risk populations
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Repeat pneumococcal polysaccharide vaccine in Indigenous Australian adults is associated with decreased immune responsivenessThese findings highlight the critical need to evaluate the efficacy of future pneumococcal vaccine programs in the Australian Indigenous populations that recommend repeated doses of 23vPPV.
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Screening for rheumatic heart disease: Quality and agreement of focused cardiac ultrasound by briefly trained health workersAfter brief training, health workers with no prior experience in echocardiography can obtain adequate quality images and make a reliable assessment
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Status of research and development of vaccines for Streptococcus pyogenesVaccines against Streptococcus pyogenes are considered as impeded vaccines because of a number of crucial barriers to development
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Changes in the clinical and epidemiological features of group A streptococcal bacteraemia in Australia's Northern TerritoryThis study adds to emerging data suggesting increasing importance of iGAS in low- and middle-income settings globally.
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Controlling acute rheumatic fever and rheumatic heart disease in developing countries: Are we getting closer?Improved opportunities for the primary prevention of ARF now exist, because of point-of-care antigen tests for Streptococcus pyogenes, and clinical decision...