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WA’s nation-leading immunisation program for babies slashes RSV hospital admissionsAn Australian-first study demonstrating the effectiveness of a new immunisation against respiratory syncytial virus (RSV) for babies found it to be almost 90 per cent effective in reducing hospitalisation rates and helped more than 500 WA families avoid a hospital stay.
Update on pneumococcal and meningococcal vaccine research
Despite the risk of having a hypo (low blood glucose levels), Gina said she refused to let T1D stop her from exercising.
Research
Empowering Social Competence: A Scoping Review of Digital Social Skills Training InterventionsEffective social skills are essential for functional social support, help-seeking, and resource access. Digital social skills training plays a key role in empowering individuals to develop social competence, improve access to various support and resources, and enhance locus of control through dynamic media.
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Phage cocktail amikacin combination as a potential therapy for bacteremia associated with carbapenemase producing colistin resistant Klebsiella pneumoniaeThe increasing occurrence of hospital-associated infections, particularly bacteremia, caused by extensively drug-resistant (XDR) carbapenemase-producing colistin-resistant Klebsiella pneumoniae highlights a critical requirement to discover new therapeutic alternatives. Bacteriophages having host-specific bacteriolytic effects are promising alternatives for combating these pathogens.
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Following in Banting’s footsteps or straying from the path? Observations from contemporary diabetes innovationWhile advancements in the treatment of diabetes continue to rapidly evolve, many of the newer technologies have financial barriers to care, opposing the egalitarian ethos of Banting who sold his patent on insulin for a nominal cost to allow it to be made widely available. Inequity in access to new therapies drives disparity in diabetes burden with potential for these gaps to widen in the future.
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Protocol of DREAM3R: DuRvalumab with chEmotherapy as first-line treAtment in advanced pleural Mesothelioma-a phase 3 randomised trialThere is a strong theoretical rationale for combining checkpoint blockade with cytotoxic chemotherapy in pleural mesothelioma and other cancers.
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A cluster randomized trial of interferon ss-1a for the reduction of transmission of SARS-Cov-2: protocol for the Containing Coronavirus Disease 19 trial (ConCorD-19)SARS-CoV-2 infection rapidly spreads in populations due to the high rates of community transmission. Interrupting the shedding of SARS-CoV-2 may reduce the incidence of Coronavirus Disease 19 (COVID-19).
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Parental pre-pregnancy BMI is a dominant early-life risk factor influencing BMI of offspring in adulthoodParental pre-pregnancy body mass index and rapid early-life weight gain predispose offspring to obesity in adulthood
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Maternity-care: measuring women’s perceptionsDevelopment of an instrument to assess women's perception of their entire maternity-care experience
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Soft neurological signs and prenatal alcohol exposure: A population-based study in remote AustraliaSoft neurological signs were more common in children with prenatal alcohol exposure or FASD, consistent with the known neurotoxic effect of PAE
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The relationship between school climate and mental and emotional wellbeing over the transition from primary to secondary schoolThe current study examined the relationship between students’ mental and emotional wellbeing and factors pertaining to school climate, focusing on the...
News & Events
Meningococcal vaccine provides extra protection for bubsIn 2017, a steep rise in cases of meningococcal disease caused by the W strain sparked a wave of concern for parents in Western Australia.
The Rio Tinto Children's Diabetes Centre is a research centre that aims to improve the lives of children and young adults living with diabetes by bringing together research, education and clinical care.
Eight-year-old Emily has type 1 diabetes, a lifelong chronic disease that requires constant management and vigilance to keep blood glucose levels on target. It is a relentless disease, not just on individuals but also on families.
News & Events
Cholesterol and blood pressure drugs help teens with diabetesThe study involved screening young people to learn more about the development of long-term kidney, eye and cardiovascular complications in adolescents with T1D.
News & Events
Telethon smashes records as West Australians dig deep for sick kidsHuge congratulations to Telethon on another record-breaking year, with generous West Australians donating just over $38 million to help sick kids.
News & Events
Two The Kids researchers appointed Academy FellowsThe Kids Researchers Professor Susan Prescott and Professor Donna Cross have been appointed Fellows of the prestigious Australian Academy of Health and Med
News & Events
Long-term The Kids Research Institute Australia researchers honoured by prestigious AcademyProfessors Carol Bower & Steve Zubrick have been inducted as new Fellows to the prestigious Australian Academy of Health and Medical Sciences.
Research
Impaired calcium influx underlies skewed T helper cell differentiation in children with IgE-mediated food allergiesReasons for Th2 skewing in IgE-mediated food allergies remains unclear. Clinical observations suggest impaired T cell activation may drive Th2 responses evidenced by increased atopic manifestations in liver transplant patients on tacrolimus (a calcineurin inhibitor). We aimed to assess differentiation potential, T cell activation and calcium influx of naïve CD4+ T cells in children with IgE-mediated food allergies.