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Research

Toxoplasma gondii infection is associated with mitochondrial dysfunction in-vitro

Our results show perturbation of host mitochondrial function following T. gondii infection that likely impacts on pathogenesis of disease.

Research

Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorder

ASD's are complex, pervasive and heterogeneous neurodevelopmental conditions with varying conditions, trajectories, significant male bias and unknown etiology.

Research

Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells

This study assessed an alternative approach, using a small scale halide assay that can be adapted for a personalized high throughput setting to analyze CFTR function of pAEC.

Research

Common and differential factors associated with abstinence and poly drug use among Australian adolescents

The aim of this study was to identify factors associated with compliance with recommendation for zero use of tobacco, alcohol and cannabis, and their use.

Research

Randomized controlled trial of text message reminders for increasing influenza vaccination

We conducted a randomized controlled trial of short message service (SMS) reminders for influenza vaccination.

Research

Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency

are oxidative stress or glutathione status associated with brochiectasis and whether glutathione deficiency is inherently linked to CF or from oxidative stress

Research

Vaccine-preventable child deaths in New South Wales from 2005 to 2014: How much is preventable?

To identify and describe potentially vaccine-preventable child deaths in New South Wales (NSW).

Research

Airway IRF7hi versus IRF7lo molecular response patterns determine clinical phenotypes in children with acute wheezing

We employed a systems biology approach to delineate upper airway gene network patterns underlying asthma exacerbation phenotypes in children.