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Here, we report on a model that does not use Th2-skewing adjuvants and yet achieves sensitization solely via the nasal mucosa.
House dust mites (HDMs) belong to the most potent indoor allergen sources worldwide and are associated with allergic manifestations in the respiratory tract.
The pathogenesis of asthma continues to be a major topic of interest to our authors with reviews and original papers on the role of viruses, mechanisms of...
The relative importance of respiratory viral infections vs inhalant allergy in asthma pathogenesis is the subject of ongoing debate.
The airway epithelium of both children and adults with asthma is relatively undifferentiated characterized by a significantly increased proportion of...
In this study, we combined human-rhinovirus infection with a clinically relevant mouse model of aero-allergen exposure using house-dust-mite in an attempt to...
The purpose of this article is to highlight emerging evidence for existing allergy prevention guidelines regarding potential benefits of supporting early...
These data highlight that antigen administration to the neonate through the oral route may contribute to child allergic sensitization and have important...
This article looks at the clinical implications of the research into microbial exposure & protection against asthma.
These findings suggest that genetic variants at the VDR locus may play a role in acute wheeze/asthma severity in children