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Association between male genital anomalies and adult male reproductive disorders: a population-based data linkage study spanning more than 40 yearsUndescended testes is associated with an increased risk of testicular cancer and male infertility, and decreased paternity
Research
An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulationTo identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins
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Genetic and environmental factors in the aetiology of hypospadiasThe increasing use of assisted reproductive techniques and hormonal manipulation during pregnancy may have been associated with an apparent rise in the...
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Comparative analysis of the full genome of Helicobacter pylori isolate sahul64 identifies genes of high divergenceGenome sequence of Sahul64, an H. pylori strain isolated from an indigenous Australian
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Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukaemiaSeveral studies suggest that maternal folic acid supplementation before or during pregnancy protects against childhood acute lymphoblastic leukaemia (ALL).
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Epitope-Binding Characteristics for Risk versus Protective DRB1 Alleles for Visceral LeishmaniasisOur data provide insight into the molecular mechanisms underpinning the association of HLA-DRB1 alleles with risk versus protection in visceral leishmaniasis in humans
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Toxoplasma gondii infection is associated with mitochondrial dysfunction in-vitroOur results show perturbation of host mitochondrial function following T. gondii infection that likely impacts on pathogenesis of disease.
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Burkholderia pseudomallei evades Nramp1 (Slc11a1)- and NADPH oxidase-mediated killing in macrophages and exhibits Nramp1-dependent virulence gene expressionHere we show that transfected macrophages stably expressing wild-type Nramp1 (Nramp1+) control the net replication of B. thailandensis, but not B. pseudomallei.
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Early childhood development of boys with genital anomaliesWe found no increased risk of poor development among boys with hypospadias or undescended testis
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Transcription start site profiling of 15 anatomical regions of the Macaca mulatta central nervous systemWe believe this data represents a useful resource to understand the central nervous system in macaque.