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Research
PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumoursOur findings define PTPN2 as a target for bolstering T-cell-mediated anti-tumour immunity and CAR T-cell therapy against solid tumours.
Research
Meningococcal B vaccine and meningococcal carriage in adolescents in AustraliaAmong Australian adolescents, the 4CMenB vaccine had no discernible effect on the carriage of disease-causing meningococci, including group B
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A structure-function analysis of interspecies antagonism by the 2-heptyl-4-alkyl-quinolone signal molecule from Pseudomonas aeruginosaHere we show that antibacterial activity of 4-hydroxy-2-heptylquinoline against Vibrionaceae is species-specific
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Fetal alcohol spectrum disorder: the importance of assessment, diagnosis and support in the Australian justice contextThe current article outlines how individuals with fetal alcohol spectrum disorder may experience inequities within the justice system
News & Events
Hon. Julie Bishop to join Human Vaccines Project boardThe Kids Research Institute Australia Chair Hon. Julie Bishop will join the international Human Vaccines Project’s Board of Directors on its mission to address the next frontier of human health – decoding the human immune system to transform how we prevent, diagnose and treat disease.
Research
Prebiotics: mechanisms and preventive effects in allergyIn this review, we describe both the mechanisms and the therapeutic evidence from preclinical and clinical studies exploring the role of prebiotics in allergy prevention
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Impact of Childhood Pneumococcal Conjugate Vaccine on Nonnotified Clinically Suspected Invasive Pneumococcal Disease in AustraliaThis study provides a quantitative estimate of the total burden of invasive pneumococcal disease preventable by vaccination programs in Australia
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The pervasive effects of timing of parental mental health disorders on adolescent deliberate self-harm riskThis study shows that timing is important for understanding intergenerational transmission of deliberate self-harm risk
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Preterm birth: Born too soon for the developing airway epitheliumThis review examines the consequences of preterm birth on the airway epithelium and explores the clinical relevance of currently available models
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Pre-emptive intervention versus treatment as usual for infants showing early behavioural risk signs of autism spectrum disorderA pre-emptive intervention for the autism spectrum disorder prodrome had no immediate treatment effect on early autism spectrum disorder symptoms