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Reconstructing the early global dynamics of under-ascertained COVID-19 cases and infectionsAsymptomatic or subclinical SARS-CoV-2 infections are often unreported, which means that confirmed case counts may not accurately reflect underlying epidemic dynamics. Understanding the level of ascertainment (the ratio of confirmed symptomatic cases to the true number of symptomatic individuals) and undetected epidemic progression is crucial to informing COVID-19 response planning, including the introduction and relaxation of control measures.
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Multiomics and Systems Biology Are Needed to Unravel the Complex Origins of Chronic DiseaseIn this concept paper, we discuss multiomic approaches to studying immune dysregulation and highlight some of the challenges and opportunities
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Use of bevacizumab as a single agent or in adjunct with traditional chemotherapy regimens in children with unresectable or progressive low-grade gliomaBevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity
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Epidemiology of intussusception before and after rotavirus vaccine introduction in FijiThe incidence of intussusception pre-rotavirus vaccine in Fiji is low
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Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed ScreensThe poor hit rates associated with conventional random peptide libraries present formidable challenges in genetic screening formats with limited throughput.
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Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cellsMature B cells, CR2/CD21 transcription proceeds from a focused TSS regulated by a non-consensus TATA box, an initiator element and downstream promoter element
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Asking QUestions about Alcohol in pregnancy (AQUA): A longitudinal cohort study of fetal effects of low to moderate alcohol exposureUsing detailed, prospective methods of data collection, the AQUA study will comprehensively examine the effects of low to moderate alcohol consumption...
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Lung function, airway inflammation, and polycyclic aromatic hydrocarbons exposure in mexican schoolchildren: A pilot studyTo determine the association of exposure to polycyclic aromatic hydrocarbons (PAHs) with lung function and pH of exhaled breath condensate (EBC) in Mexican...
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Making a difference: Engaging both hearts and minds in research practiceThis paper discusses the findings and the research process undertaken thus far for the Looking Forward Aboriginal Mental Health Project.
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Yarning about yarning as a legitimate method in Indigenous ResearchThis article demonstrates the credibility and rigor of yarning, an Indigenous cultural form of conversation, through its use as a data gathering tool