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Research

House Dust Mite Allergens: New Discoveries and Relevance to the Allergic Patient

Recent findings on house dust allergens and their contribution to knowledge that will significantly impact current and future allergy treatments are appraised

Research

Western environment/lifestyle is associated with increased genome methylation and decreased gene expression in Chinese immigrants living in Australia

Chinese immigrants living in Australia for a longer period of time have increased overall genome methylation and decreased overall gene expression

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Chronic cat allergen exposure induces a Th2 cell-dependent IgG4 response related to low sensitization

This study evaluated the relationship between cat allergen–specific biomarkers in adults with cat allergy with and without cat ownership.

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Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised children

We aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked.

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Structural and IgE binding analyses of recombinant Der p 2 expressed from the hosts Escherichia coli and Pichia pastoris

The house dust mite allergen Der p 2 is one of the most important indoor allergens associated with allergic disease.

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House dust mite allergens in asthma and allergy

IgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against

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Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite Allergen

The mutant Der p 2 had altered structure and reduced ability to stimulate pro-inflammatory responses and to bind IgE

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Investigations into the role of ST2 in acute asthma in children

This study investigated the potential role of ST2 in children with acute asthma.

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Reduced rhinovirus-specific antibodies are associated with acute exacerbations of chronic obstructive

Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are often linked to respiratory infections.

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House dust allergy and immunotherapy

HDM allergy is associated with asthma, allergic rhinitis and atopic dermatitis.