Water chlorination is essential for controlling harmful microbes in drinking water; however, the antimicrobial effects of chlorine-based disinfectant…
Previous research has shown that immune development during the first week of life, i.e. ontogeny, is progressive, consistent and robust, involving la…
We investigated the genetic and epigenetic regulation of the UBASH3A gene and its association with early-onset sepsis. Using matched whole blood DNA…
Protection of newborns from infection can be achieved through maternal or vaccine-induced antibodies, but the factors influencing vaccine protection…
Human milk is a rich source of immunomodulatory factors that influence the development of the infant immune system, including susceptibility to aller…
Dynamic molecular changes in early life follow a robust ontogeny as the infant immune system adapts to the demands of its new environment. Studies of…
Type 1 interferons (T1IFNs) are typically expressed in low concentrations under homeostatic conditions, but upon pathogenic insult or perturbation of…
Food allergy affects families' quality of life, can be lifelong and life-threatening, urging the identification of early modifiable risk factors. For…
First-of-its-kind findings show that newborns exclusively fed colostrum in their first 72 hours of life were five times less likely to develop a pean…
Immunomodulatory proteins in human milk (HM) can shape infant immune development. However, strategies to modulate their levels are currently unknown.…