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Research

Sex assigned at birth may modify health-related quality of life in children treated with peanut oral immunotherapy

The high burden of peanut allergy underscores the need for treatment options that improve patient health-related quality of life (HRQL). However, the modifying effect of sex assigned at birth on treatment-related outcomes remains poorly understood. We sought to investigate whether sex modifies treatment effect on the change in overall and subdomain HRQL during the PPOIT-003 trial.

Research

DeepEGFR a graph neural network for bioactivity classification of EGFR inhibitors

Epidermal Growth Factor Receptor (EGFR) plays a critical role in the development of several cancers. Thus, modulation/inhibition of EGFR activity is an appealing target of developing novel cancer therapeutics. 

Cutting-edge CliniKids keeps families up-to-date

CliniKids, the first stand-alone clinical service offered by The Kids Research Institute Australia, was launched in October 2019 and is already delivering benefits for families with children who are developing differently.

Trial aims to improve survival rates for kids with brain cancer

An international clinical trial led by The Kids Research Institute Australia Cancer Centre is trialling a drug which could increase cure rates for aggressive forms of childhood brain cancer.

The bonus feature giving ORIGINS participants a head start on health issues

The ORIGINS Project, a collaboration between The Kids and Joondalup Health Campus, is collecting data and biological samples from 10,000 families over 10 years. Its work is also giving participating families a valuable heads up on health issues.

Alcohol warning labels a win for Australian babies

Strong advocacy efforts have paid off with health and food safety ministers from around Australia and New Zealand finally approving the recommended version of a warning label designed to highlight the potential risks of alcohol during pregnancy.

Don’t stop her now – Gina’s having a ball

Despite the risk of having a hypo (low blood glucose levels), Gina said she refused to let T1D stop her from exercising.

Research

Developmental Coordination Disorder

Developmental Coordination Disorder is a lifelong disability impacting most aspects of daily living that involve movement. With an estimated prevalence of ~5% of children, the disorder affects an average of one to two children in every Australian classroom.

Research

School Attendance

Each day of school missed makes a difference, with the effect on learning accumulating over time. From an early age, if children are taught that they need to 'show up' for school and make a commitment, this positive mentality aids academic and career success and brings benefits in adulthood.

Impact: In the Pipeline

On this Research Impact page, we list stories helping to show our exciting in-progress research currently "in the pipeline" towards translation. This is research which shows a real spark of potential to make a significant difference to children and families worldwide.