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Defective aeroallergen surveillance by airway mucosal dendritic cells as a determinant of riskA hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial...
Research
Small macrophages are present in early childhood respiratory diseaseRecently, an established "small macrophage" phenotype has been observed in the sputum of patients with CF and COPD. However, little is known about the...
Adolescence can be challenging for all kids, but especially for those who are Deaf or hard-of-hearing. New resources developed by The Kids Research Institute Australia aim to make life a little easier.
Can young people experiencing homelessness be part of the solution in suicide prevention? That is the question youth mental health researchers at Embrace at The Kids Research Institute Australia will investigate.
When KEMH specialists first suggested using coconut oil to treat the fragile skin of Kimberly Rohrlach’s extremely premature first-born child, Isabella, she thought it was more than a little weird.
Results from a world first-study measuring prevalence of chronic wet cough and protracted bacterial bronchitis in four Kimberley Aboriginal communities have highlighted the enormity of the health problem.
Research
Decreased Physical Working Capacity in Adolescents With Nonalcoholic Fatty Liver Disease Associates With Reduced Iron AvailabilityIn a well-defined cohort of adolescents, we found non-alcoholic fatty liver disease to be associated with decreased cardiorespiratory fitness, independent of BMI
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Human genetics of leishmania infectionsGWAS results provide firm confirmation for the importance of antigen presentation and the regulation of IFNγ in determining the outcome of Leishmania infections
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Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflowsSystematic comparison of recovered cell types and their transcriptional profiles across the workflows has highlighted protocol-specific biase
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COPD-related modification to the airway epithelium permits intracellular residence of nontypeable haemophilus influenzaeOur findings indicate that COPD, cigarette smoke and macrolide antibiotics potentiate the susceptibility to persistent intracellular NTHi