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Research

Whole-cell pertussis vaccine in early infancy for the prevention of allergy

This is a protocol for a Cochrane Review (intervention). The objectives were to assess the efficacy and safety of whole‐cell pertussis (wP) vaccinations in comparison to acellular pertussis (aP) vaccinations in early infancy for the prevention of atopic diseases in children.

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Constitutive Activation of RAS/MAPK Pathway Cooperates with Trisomy 21 and Is Therapeutically Exploitable in Down Syndrome B-cell Leukemia

Children with Down syndrome (constitutive trisomy 21) that develop acute lymphoblastic leukemia (DS-ALL) have a 3-fold increased likelihood of treatment-related mortality coupled with a higher cumulative incidence of relapse, compared with other children with B-cell acute lymphoblastic leukemia (B-ALL).

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Golden Age of Medicine 2.0: Lifestyle Medicine and Planetary Health Prioritized

We emphasize that barriers to planetary health and the clinical application of lifestyle medicine are maintaining an unhealthy status quo

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RD-RAP: Beyond rare disease patient registries, devising a comprehensive data and analytic framework

We introduce and describe the concept of a Rare Disease Registry and Analytics Platform

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Trends in mental health related contacts among mothers of Aboriginal children in Western Australia (1990-2013)

Many of the mental health issues that women develop earlier in life are chronic at the time of conception, during pregnancy and at birth

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Vitamin and mineral supplements: Gut health and probiotics: Probiotics for a healthy microbiome: An evidence-based approach to appropriate product choice

This review discusses the available evidence base to help provide practical guidance when considering probiotics in practice

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Dietary protein affects both the dose and pattern of insulin delivery required to achieve postprandial euglycaemia in Type 1 diabetes: a randomized trial

A high-protein meal requires ~50% more insulin to maintain euglycaemia than a low-protein meal that contains the same quantity of carbohydrate

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Common Pathways to NSSI and Suicide Ideation: The Roles of Rumination and Self-Compassion

The salience of self-compassion offers promise for early intervention initiatives focusing on less judgmental or self-critical means of self-relation

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Community-based participatory action research on rheumatic heart disease in an Australian Aboriginal homeland: Evaluation of the ‘On track watch’ project

Based in 'both-way learning', the aim of this study was to co-design, implement and evaluate community-based participatory action research to achieve this vision