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Research
Systematic In Vitro Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged LeukemiaPatients whose leukemias harbor a rearrangement of the Mixed Lineage Leukemia (MLL/KMT2A) gene have a poor prognosis, especially when the disease strikes in infants. The poor clinical outcome linked to this aggressive disease and the detrimental treatment side-effects, particularly in children, warrant the urgent development of more effective and cancer-selective therapeutics.
News & Events
Bone density treatment found to slow the progression of leukaemiaThe Kids Research Institute Australia researchers may have unlocked a vital key to reducing the progression of leukaemia in children, potentially prompting a change in thinking around the best way to target treatment.
News & Events
Researchers receive crucial Near Miss fundingCongratulations to four outstanding The Kids Research Institute Australia researchers who have received funding designed to support researchers who have narrowly missed out on highly competitive national funding.
The main aim of our Leukaemia Translational Research Team is to test innovative therapeutic approaches, with a focus on clinical translation of this knowledge, to improve the outcomes of children suffering from leukaemia.
The Translational Genomics in Leukaemia team is focused on identifying the causes of leukaemia, with the goal of developing new targeted treatments to improve quality of care and long-term survival for all children with leukaemia.
Research
Children's CancersCancers in children are very different from cancers in adults - in most cases they appear to strike simply at random. They also develop differently and can spread more rapidly and aggressively. And because cancers in children are not obviously linked to their lifestyles, much work is needed to pinpoint their cause.
Research
Chronic carbon dioxide exposure: an unrecognised health risk of climate change?Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate
The CIRCA DIEM Study is a clinical research study being coordinated by the Neonatal Cardiorespiratory Team at The Kids Research Institute Australia, who are based in Perth, Western Australia and involving research teams from around the world.
The CIRCA DIEM study is a multicentre, prospective, open, blinded end-point (PROBE) parallel controlled study which aims to compare long term neuro-developmental outcomes of premature babies cared for in a cycled environment to premature babies who receive routine care in a non-cycled environment.
Research
Cochrane CSOM: A suite of reviews examining the effectiveness of interventions to treat chronic suppurative otitis media (CSOM) globallyChris Peter Brennan-Jones Richmond C PC PhD MBBS MRCP(UK) FRACP Head, Ear Health Head, Vaccine Trials Group chris.brennan-jones@telethonkids.org.au