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Caregiver-Mediated Early Support Program Delivered Online Versus Care-as-Usual for Infants at Elevated Familial Likelihood for AutismLiL' STEPS (Language development & Intervention Lab's SupporTing Early social-communication and language by Promoting caregiver Sensitive responsiveness) is a novel, manualized, caregiver-mediated early support program developed in India and delivered online for infants at elevated familial likelihood for autism. The program has been found to be feasible and acceptable. The preliminary efficacy of the LiL' STEPS program, which remains to be evaluated, was assessed in this study using a feasibility randomized controlled trial design.
Research
Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genesWe performed a genome-wide association meta-analysis of 290,134 attention-deficit/hyperactivity disorder symptom measures of 70,953 unique individuals from multiple raters, ages and instruments.
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Multimillion-dollar ORIGINS Project recruits 1000th family for global health studyProfessor Desiree Silva with the 1000th family - Jess, Michael and Eli The multimillion-dollar ORIGINS Project, an extensive community-based
Research
Egg-sensitised infants have elevated CD4+ effector memory T regulatory cells from birthIgE-mediated sensitisation to egg is common in infants. In some cases, the processes leading to egg sensitisation are established in early life, even before introduction to solid foods. The underlying mechanisms remain poorly understood.
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Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA studyImmunomodulatory proteins in human milk (HM) can shape infant immune development. However, strategies to modulate their levels are currently unknown. This study investigated whether maternal prebiotic supplementation alters the levels of immunomodulatory proteins in HM.
Research
Mums Minds MatterAmy Jenny Susan Desiree Keerthi Finlay-Jones Downs Prescott Silva Kottampally BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) BApplSci
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Child health and obesity the focus of international built environment studyResearch data from more than one million Australian and Welsh children will be examined to help better understand how the built environment affects child health and obesity, as part of an international research project to be co-led by The Kids Research Institute Australia.
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Bone density treatment found to slow the progression of leukaemiaThe Kids Research Institute Australia researchers may have unlocked a vital key to reducing the progression of leukaemia in children, potentially prompting a change in thinking around the best way to target treatment.
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Researchers receive crucial near miss fundingCongratulations to three outstanding The Kids Research Institute Australia researchers who have received second chance WA health funding designed to support researchers who have narrowly missed out on highly competitive national funding.
Research
Children's CancersCancers in children are very different from cancers in adults - in most cases they appear to strike simply at random. They also develop differently and can spread more rapidly and aggressively. And because cancers in children are not obviously linked to their lifestyles, much work is needed to pinpoint their cause.