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Research

Lower HbA1c targets are associated with better metabolic control

Previous studies have suggested that clear HbA1c target setting by the diabetes team is associated with HbA1c outcomes in adolescents. The aim of this study was to evaluate whether this finding is consistent in a larger cohort of children from centers participating in the SWEET international diabetes registry. A questionnaire was sent out to 76 SWEET centers, of which responses from 53 pediatric centers were included (70%). Descriptive outcomes were presented as median with lower and upper quartile.

Research

School-based HPV vaccination positively impacts parents’ attitudes toward adolescent vaccination

This qualitative study aimed to explore parental attitudes, knowledge and decision-making about HPV vaccination for adolescents in the context of a gender-neutral school-based Australian National Immunisation Program (NIP). Semi-structured interviews with parents of adolescents eligible for HPV vaccination were undertaken as part of an evaluation of a cluster-randomised controlled trial of a complex intervention in 40 schools (2013-2015).

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The high prevalence and impact of rheumatic heart disease in pregnancy in First Nations populations in a high-income setting: a prospective cohort study

Rheumatic heart disease in pregnancy persists in First Nations people in Australia and New Zealand and is associated with major cardiac and perinatal morbidity

Research

A broad autism phenotype expressed in facial morphology

These data provide the first evidence for a broad autism phenotype expressed in a physical characteristic

Research

Online self-compassion training to improve the wellbeing of youth with chronic medical conditions: Protocol for a randomised control trial

The Self-Compassion Online program could provide a scalable solution for improving psychological outcomes and quality of life among youth with chronic illness

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Priorities for improved management of acute rheumatic fever and rheumatic heart disease

The results suggest that timely injection and patient education are priorities for managing ARF and RHD, particularly focusing on child-to-adult transition care.

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Qualitative study of psychosocial factors impacting on Aboriginal women's management of chronic disease

The caring roles and responsibilities Aboriginal women have in their community impact on their health

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Harmonised collection of data in youth mental health: Towards large datasets

The use of this core set of data will facilitate the pooling of psychopathological and neurobiological data into large datasets

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Immune-mediated ECM depletion improves tumour perfusion and payload delivery

We have devised a new approach to degrade tumour ECM, which improves uptake of circulating compounds

Research

Tumor necrosis factor α induces α1B-adrenergic receptor expression in keratinocytes

Our results suggest that inflammatory cytokines released during injury stimulate α1-AR expression in keratinocytes