Search
See the latest ORIGINS news.
News & Events
The First 1,000 DaysThis article explores how to support a child's physical and mental health during critical developmental periods, known as the first 1,000 days of life.
News & Events
New Funding Supports ORIGINS’ Expansion into Early Childhood ResearchThe ORIGINS Project has been named as a key beneficiary of the Stan Perron Charitable Foundation Research People & Platform round for 2023.
News & Events
ORIGINS Enters the Shark TankORIGINS Biobank Manager wins a Shark Tank pitch at Scientific Retreat
News & Events
ORIGINS Biobank Manager is inspiring women and girlsMeet Dr Nina D’Vaz, ORIGINS Biobank Manager who recently featured in The Kids Research Institute Australia's social media celebration of International Women and Girls in Science Day.
Get in Touch Dropping off a sample or attending a Kids Check appointment? Visit us at our Edgewater clinic. The Kids Joondalup Shop 51, Joondalup
Research
Initial Validation and Reliability of the CDKL5 Deficiency Disorder Hand Function Scale (CDD-Hand)Pathogenic variants in the CDKL5 gene result in CDKL5 deficiency disorder (CDD), which is characterized by early-onset epilepsy, severe developmental delay, and often, cortical visual impairment. Validated clinical outcome measures are needed for future clinical trials to be successful. This study aimed to adapt the Rett Syndrome Hand Function Scale for CDKL5 deficiency disorder and evaluate its feasibility, acceptability, content validity, and reliability.
Research
Resilience and Posttraumatic Growth after Burn: A Review of Barriers, Enablers, and Interventions to Improve Psychological RecoveryBurn injuries are traumatic experiences that can detrimentally impact an individual’s psychological and emotional wellbeing. Despite this, some survivors adapt to psychosocial challenges better than others despite similar characteristics relating to the burn.
Research
Two cases of Leclercia adecarboxylata septic arthritis in immunocompetent paediatric patientsLeclercia adecarboxylata is a rare cause of septic arthritis in children, and has intrinsic resistance to common antibiotics. We describe two cases of L. adecarboxylata septic arthritis in children that required re-presentation to hospital with prolonged treatment, and highlight the importance of considering L. adecarboxylata as a potential cause of infection among children with penetrating injuries and associated environmental exposure.
Research
Circulating Memory B Cells in Early Multiple Sclerosis Exhibit Increased IgA+ Cells, Globally Decreased BAFF-R Expression and an EBV-Related IgM+ Cell SignatureMultiple sclerosis (MS) is an immune-mediated inflammatory disease of the central nervous system that results in demyelination of axons, inefficient signal transmission and reduced muscular mobility. Recent findings suggest that B cells play a significant role in disease development and pathology. To further explore this, B cell profiles in peripheral blood from 28 treatment-naive patients with early MS were assessed using flow cytometry and compared to 17 healthy controls.