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Research

MK2 inhibition induces p53-dependent senescence in glioblastoma cells

In response to DNA damaging chemotherapy, targeting MK2 in p53-mutated cells produces a phenotype that is distinct from the p53-deficient phenotype

Research

Maternal HIV infection alters antimicrobial immunity in exposed and uninfected infants

Implementation of lifelong ART of all HIV-infected women has the potential to improve maternal determinants of protective immunity in the young infant

Research

Genome-wide association meta-analysis of single-nucleotide polymorphisms and symptomatic venous thromboembolism during therapy for ALL and lymphoma in caucasian children

The largest GWAS meta-analysis conducted to date associating SNPs to venous thromboembolism in children and adolescents treated on childhood ALL protocols

Research

Priorities for improved management of acute rheumatic fever and rheumatic heart disease

The results suggest that timely injection and patient education are priorities for managing ARF and RHD, particularly focusing on child-to-adult transition care.

Research

Qualitative study of psychosocial factors impacting on Aboriginal women's management of chronic disease

The caring roles and responsibilities Aboriginal women have in their community impact on their health

Research

Harmonised collection of data in youth mental health: Towards large datasets

The use of this core set of data will facilitate the pooling of psychopathological and neurobiological data into large datasets

Research

Immune-mediated ECM depletion improves tumour perfusion and payload delivery

We have devised a new approach to degrade tumour ECM, which improves uptake of circulating compounds

Research

Tumor necrosis factor α induces α1B-adrenergic receptor expression in keratinocytes

Our results suggest that inflammatory cytokines released during injury stimulate α1-AR expression in keratinocytes

Research

Child and adolescent psychiatry training in Australia and New Zealand

This article highlights the requirements of the training programs for Child and Adolescent Psychiatry in Australia and New Zealand

Research

Resilience and Posttraumatic Growth after Burn: A Review of Barriers, Enablers, and Interventions to Improve Psychological Recovery

Burn injuries are traumatic experiences that can detrimentally impact an individual’s psychological and emotional wellbeing. Despite this, some survivors adapt to psychosocial challenges better than others despite similar characteristics relating to the burn.