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How many doses make a difference? An analysis of secondary prevention of rheumatic fever and rheumatic heart diseaseincreased adherence to penicillin prophylaxis is associated with reduced acute rheumatic fever recurrence and a likely reduction in mortality
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Autism and intellectual disability are differentially related to sociodemographic background at birthWe used population data on Western Australian singletons born from 1984 to 1999 (n = 398,353) to examine the sociodemographic characteristics of children...
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Insulin Pump Therapy in Adolescents With Very Poor Glycemic Control During a 12-Month Cohort TrialWe conclude that insulin pump therapy can be an effective tool to improve glycemic control in adolescents with long-standing treatment resistance
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In utero cigarette smoke exposure impairs somatic and lung growth in BALB/c miceThe aim of this study was to assess whether in utero tobacco smoke exposure alone affects early-life lung growth and development. Pregnant BALB/c mice...
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Conserved temporal ordering of promoter activation implicates common mechanisms governing the immediate early response across cell types and stimuliWe obtain a set of 57 candidate immediate early genes possessing promoters that consistently drive a rapid but transient increase in expression over time
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Plasma versus serum levels of osteopontin and mesothelin in patients with malignant mesothelioma-Which is bestBlood-based markers for malignant mesothelioma (MM), particularly soluble mesothelin and osteopontin, are currently of great clinical interest.
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CrossTalk opposing view: Mucosal acidification does not drive early progressive lung disease in cystic fibrosisWhether airway mucosal acidification drives early progressive lung disease is controversial
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Global strategy for the diagnosis and management of asthma in children 5 years and youngerAsthma is the most common chronic disease of childhood and the leading cause of childhood morbidity from chronic disease as measured by school absences...
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The Gender Wage Gap in the Vietnamese Transition, 1993–2008This essay examines wages and the gender wage gap between 1993 and 2008 in Vietnam
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Prenatal stress and risk of behavioral morbidity from age 2 to 14 years:The maternal experience of stressful events during pregnancy has been associated with a number of adverse consequences for behavioral development offspring...
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Fetal Alcohol Spectrum DisorderSupports healthcare professionals to understand how to make a diagnosis of FASD and to provide support for those diagnosed with FASD
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The effectiveness of enhanced cognitive behavioural therapy for eating disorders: An open trialThe aim of this study was to examine the effectiveness of Enhanced Cognitive Behaviour Therapy (CBT-E) for eating disorders in an open trial for adults...
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Burden of skin disease in two remote primary healthcare centres in northern and central AustraliaSkin infections are an under-appreciated and dominant reason for presentation to primary healthcare centres in these indigenous communities
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Randomised controlled trial analysing supplementation with 250 versus 500 units of vitamin D3, sun exposure and surrounding factors in breastfed infantsThe rate of non-compliance with vitamin D supplementation is as high as 45%. This is why randomised controlled trials are needed to analyse the response...
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Association between male genital anomalies and adult male reproductive disorders: a population-based data linkage study spanning more than 40 yearsUndescended testes is associated with an increased risk of testicular cancer and male infertility, and decreased paternity
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Changes in the FEV/FVC ratio during childhood and adolescence: an intercontinental studyIn children, the ratio of forced expiratory volume in 1 s (FEV₁) to forced vital capacity (FVC) is reportedly constant or falls linearly with age...
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Incidence and prevalence of falls in adults with intellectual disability living in the community: a systematic reviewSynthesized findings demonstrate that people with intellectual disability, who live in community or residential settings, may fall more frequently, and at a younger age
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A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1To identify new susceptibility loci for psoriasis, we undertook a genome-wide association study of 594,224 SNPs in 2,622 individuals with psoriasis...
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Use of bevacizumab as a single agent or in adjunct with traditional chemotherapy regimens in children with unresectable or progressive low-grade gliomaBevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity