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Research

Rheumatic Heart Disease Worldwide: JACC Scientific Expert Panel

The authors present a variety of pressing clinical research questions on optimal RHD prevention and advanced care

Research

Worldwide variation in human milk metabolome: Indicators of breast physiology and maternal lifestyle?

This study investigates the variation of human milk metabolites in human milk between five different countries

Research

The Canmore Declaration: Statement of Principles for Planetary Health

We provide the Canmore Declaration, a Statement of Principles for Planetary Health

Research

Teleaudiology services for rehabilitation with hearing aids in adults: A systematic review

This review provides up-to-date evidence for teleaudiology hearing aid services in new and experienced hearing aid users in different practice settings

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IgE and T-cell responses to house dust mite allergen components

Recent studies with synthetic peptides representing allergens and non-allergenic house dust mite proteins now offer new research avenues on HDM induced immune responses

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Epigenetic dysregulation of naive CD4+ T-cell activation genes in childhood food allergy

Our data indicate epigenetic dysregulation in the early stages of signal transduction through the T cell receptor complex, and likely reflects pathways modified by gene-environment interactions in food allergy

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Relevance of Aboriginal Peer-Led Parent Support: Strengthening the Child Environment in Remote Areas

This research highlights the critical emerging role of peer support workers in home visiting family support in a remote area of Australia

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Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions

This is the first report examining the role of different rhinovirus species in ARIs in children admitted to a tertiary PICU

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Duration of general anaesthetic exposure in early childhood and long-term language and cognitive ability

Anaesthetic dose causing toxicity in animals has been evaluated, but the relationship between duration of VA exposure and development in children remains vague.

Research

PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo

Our results reveal long-lasting changes to progenitor cells of monocytes/macrophages by a 2-hour dimethyl PGE2 pulse that, in turn, limits the migration of their daughter cells to chemoattractants and inflammatory mediators.