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Research

Challenges to curing primary brain tumours

The seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment in brain tumours

Research

Folate Status and Neural Tube Defects in Aboriginal Australians: The Success of Mandatory Fortification in Reducing a Health Disparity

Mandatory flour fortification with folic acid in 2009, led to further reductions in overall neural tube defects

Research

The epidemiological transition in Papua New Guinea: new evidence from verbal autopsy studies

Our results indicate immediate priorities for health service planning and for strengthening of vital registration systems

Research

Potential use of Western Australia’s mandatory Midwives Notification System for routinely monitoring antenatal vaccine coverage

We observed low sensitivity and specificity of antenatal vaccination data in the Midwives Notification System

Research

Lessons learned from a hospital-wide review of blood stream infections for paediatric central line-associated blood stream infection prevention

Health care-associated bacteraemia has a significant impact on child health, exceeding the number of community-acquired bacteraemia at our hospital

Research

The Challenges of Being Physically Active: A Qualitative Study of Young People With Type 1 Diabetes and Their Parents

Benefits of physical activity are well recognized for youth with type 1 diabetes mellitus (T1DM), but being active is challenging. In this study, we aimed to investigate the challenges experienced by adolescents, their parents and young adults with T1DM when they are physically active.

Research

Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia

Our study provides evidence that OT-82 is a promising new therapeutic strategy for a broad spectrum of high-risk pediatric acute lymphoblastic leukemia

Research

Understanding obesity among companion dogs: New measures of owner's beliefs and behaviour and associations with body condition scores

The findings provide a method for assessing a wide range of factors that may be associated with obesity among companion dogs

Research

SNAIL trail in myeloid malignancies

Transcription factors known to induce the epithelial-to-mesenchymal transition (EMT) (such as ZEB1/2 [zinc finger E-box binding homeobox 1/2], SNAI1/2/3, and TWIST1/2) have been undoubtedly implicated in tumorigenesis, cancer progression, metastasis, and chemoresistance in solid tumors; however, their role in normal and malignant hematopoiesis has been underappreciated for many years.

Research

The Demographic and Neurocognitive Profile of Clients Diagnosed With Fetal Alcohol Spectrum Disorder in PATCHES Paediatrics Clinics

The aim of this study was to describe the demographic and neurocognitive profile of the first 199 individuals diagnosed with FASD in PATCHES Paediatrics clinics