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Research

The Perth Empathy Scale: Psychometric Properties of the Polish Version and Its Mental Health Correlates

The Perth Empathy Scale (PES) is a 20-item self-report questionnaire that assesses people's ability to recognize emotions in others (i.e., cognitive empathy) and vicariously experience other's emotions (i.e., affective empathy), across positive and negative emotions. Originally developed in English, the aim of our study was to introduce the first Polish version of the PES and test its psychometric performance.

Research

Global prevalence of psychiatric in- and out-patient treatment following hospital-presenting self-harm: a systematic review and meta-analysis

Hospital-treated self-harm is common, costly, and strongly associated with suicide. Whilst effective psychosocial interventions exist, little is known about what key factors might modify the clinical decision to refer an individual to psychiatric in- and/or out-patient treatment following an episode of hospital-treated self-harm.

Research

Surfacing undiagnosed disease: consideration, counting and coding

The diagnostic odyssey for people living with rare diseases (PLWRD) is often prolonged for myriad reasons including an initial failure to consider rare disease and challenges to systemically and systematically identifying and tracking undiagnosed diseases across the diagnostic journey.

Linked data and process

Data linkage is a technique for connecting pieces of information that are thought to relate to the same person, family, place or event.

Research

Perspectives on the essential skills of healthcare decision making in children and adolescents with intellectual disability

Involvement in healthcare decisions is associated with better health outcomes for patients. For children and adolescents with intellectual disability, parents and healthcare professionals need to balance listening to a child's wishes with the responsibility of keeping them safe. 

Research

Perspectives of LGBTQA+ young people on suicide prevention services in Australia

LGBTQA + people are less likely to access mental health care despite an increased risk of adverse mental health outcomes including suicidal thoughts and behaviours. The present study aimed to explore Australian LGBTQA + young people's perceptions of key factors associated with access to suicide prevention services.

Research

Minimising Adverse Drug Reactions and Verifying Economic Legitimacy-Pharmacogenomics Implementation in Children (MARVEL- PIC): protocol for a national randomised controlled trial

DNA-informed prescribing (termed pharmacogenomics, PGx) is the epitome of personalised medicine. Despite international guidelines existing, its implementation in paediatric oncology remains sparse.

Research outputs

Find out about the research outputs for the Development Pathways Project, and see the published research outcomes.

Research

Unique architectural features of mammalian mitochondrial protein synthesis

Mitochondria rely on coordinated expression of their own mitochondrial DNA (mtDNA) with that of the nuclear genome for their biogenesis. The bacterial ancestry of mitochondria has given rise to unique and idiosyncratic features of the mtDNA and its expression machinery that can be specific to different organisms. In animals, the mitochondrial protein synthesis machinery has acquired many new components and mechanisms over evolution.

Report: Pathways of young people in contact with multiple government agencies in Western Australia

Findings of a research study examining the characteristics of service use by a cohort of young people born between 1994-1997 who used four government services.

Research

Illuminating mitochondrial translation through mouse models

Mitochondria are hubs of metabolic activity with a major role in ATP conversion by oxidative phosphorylation (OXPHOS). The mammalian mitochondrial genome encodes 11 mRNAs encoding 13 OXPHOS proteins along with 2 rRNAs and 22 tRNAs, that facilitate their translation on mitoribosomes.

Research

Ear Explorers: A ‘real-life research project’ enabling children to view inside their own ears using smartphone video-otoscopy

Chris Brennan-Jones PhD Head, Ear and Hearing Health chris.brennan-jones@thekids.org.au Head, Ear and Hearing Health Professor Chris Brennan-Jones is

Research

Evaluation of the Fetal Alcohol Spectrum Disorder Hub Australia website

To evaluate use and utility of the Fetal Alcohol Spectrum Disorder (FASD) Hub Australia website. 

Research

Engineering new tools to improve energy metabolism

Aleksandra Filipovska BSc PhD Louis Landau Chair in Child Health Research; NHMRC Leadership Fellow; Deputy Director, ARC Centre of Excellence for

Research

Global fertility in 204 countries and territories, 1950-2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

Accurate assessments of current and future fertility-including overall trends and changing population age structures across countries and regions-are essential to help plan for the profound social, economic, environmental, and geopolitical challenges that these changes will bring. Estimates and projections of fertility are necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality, and family planning and support. 

Research

Fetal alcohol exposure, nutritional status and epigenetic disruption – exploring the links

Alexander David Martyn Larcombe Martino Symons BScEnv (Hons) PhD BSc PhD B.A. (Hons) PhD. Honorary Research Fellow Head, Chronic Diseases Research

Research

Game Changers project

The Game Changers project was about using the Kimberley passion and enthusiasm for sport to engage Kimberley kids who were in a disrupted environment, with negative impacts on behaviour and attendance at school, leaving them vulnerable and at-risk in the community.

Research

Geospatial analysis of Japanese Encephalitis virus (JEV) transmission risk

Japanese Encephalitis virus is a mosquito-borne virus that is typically only found in south-east Asia.

Research

Geospatial modelling for malaria risk stratification and intervention targeting for low-endemic countries

Ewan Punam Susan Tasmin Cameron Amratia Rumisha Symons BSc PhD PhD PhD (Biostatistics) Director of Malaria Risk Stratification Honorary Research

Research

Giving Voice to Rural and Regional Boys and Young Men and Supporting Parents to Prevent Tech-Based Abuse of Girls and Young Women

This project addresses the growing issue of technology-facilitated abuse against women and girls, particularly in regional Western Australian communities where risks are heightened, and access to support is limited.