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Alpha-1 antitrypsin mitigates the inhibition of airway epithelial cell repair by neutrophil elastaseFree NE activity is deleterious for epithelial homeostasis and support the hypothesis that proteases in the airway contribute to CF structural lung disease
Research
Rapid recruitment of CD14+ monocytes in experimentally induced allergic rhinitis in human subjectsMononuclear phagocyte population is directly involved in the production of proinflammatory chemokines that attract other immune cells
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Adverse metabolic phenotype of adolescent girls with non-alcoholic fatty liver disease plus polycystic ovary syndrome compared with other girls and boysNon-alcoholic fatty liver disease (NAFLD) and polycystic ovary syndrome (PCOS) share risk associations of adiposity and insulin resistance.
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Strabismus, a preventable barrier to social participation: A short reportIsolated strabismus does not significantly impair visual functionality and has traditionally been considered a primarily cosmetic defect of little importance.
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Relationship between early motor milestones and severity of restricted and repetitive behaviors in children and adolescents with autism spectrum disorderThis study provides the first evidence for the association between restricted and repetitive behaviors and age of attainment of early motor milestones.
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Are scabies and impetigo “normalised”? A cross-sectional comparative study of hospitalised children in northern Australia assessing clinical recognitionScabies and impetigo infections are under-recognised and hence under-treated by clinicians
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A novel technique of serial biopsy in mouse brain tumour modelsHere we describe a method by which serial biopsy can be used to validate response to dacomitinib treatment in vivo using a mouse glioblastoma model
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Sub-erythemal ultraviolet radiation reduces metabolic dysfunction in already overweight miceExposure to sunlight may limit cardiometabolic risk.
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Umbilical cord androgens and estrogens in relation to verbal and nonverbal abilities at age 10 in the general populationThese data suggest that late gestation sex steroids do not exert a major effect on nonverbal and verbal abilities in middle childhood.
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International consensus (ICON) on: Clinical consequences of mite hypersensitivity, a global problemThe objectives of this document are to highlight aspects of mite biology that are clinically relevant and to update the current knowledge on mite allergens