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Research

The safety and feasibility of the inhaled mannitol challenge test in young children

Mannitol challenge tests are used clinically to diagnose asthma and, in particular, exercise-induced broncoconstriction (EIB) in adults and children above 6...

Research

The effect of diesel exhaust exposure on blood-brain barrier integrity and function in a murine model

Epidemiological studies indicate that exposure to diesel exhaust (DE) is associated with vascular-based disorders.

Research

A conceptual framework for comprehensive rheumatic heart disease control programs

The World Health Organization, World Heart Federation, and other organizations recommend comprehensive control programs for rheumatic fever (RF) and...

Research

Antecedents of cerebral palsy and perinatal death in term and late preterm singletons

The odds of total cerebral palsy after potentially asphyxial birth events or inflammation were modestly increased.

Research

Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children

The present study aimed to clarify the effect of viral and bacterial co-detections on disease severity during paediatric acute respiratory infection (ARI).

Research

Linking FANTOM5 CAGE peaks to annotations with CAGEscan

Here, we present the production and quality control of CAGEscan libraries from 56 FANTOM5 RNA sources

Research

Broad perspectives of allergen specific immunotherapy

Allergen specific immunotherapy aims to subvert or divert immune responses to allergens to ones that do not cause immunological hypersensitivities.

Research

Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers

We sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception.

Research

Alcohol consumption in a general antenatal population and child neurodevelopment at 2 years

This study examines the association between PAE in the general antenatal population and child neurodevelopment at 2 years, accounting for relevant factors.