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Research
Pre-onset risk characteristics for mania among young people at clinical high risk for psychosisWe aimed to identify the rate and predictors of transition to mania in a cohort of youth with clinical or familial risk for psychosis.
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Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool childrenWe characterized the lower airways microbiome using BAL samples obtained from clinically stable CF young children who underwent bronchoscopy and chest CT.
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Prominent IgE-binding and cytokine-inducing capacities of a newly cloned N-terminal region of Der f 14, an apolipophorin-like house dust mite allergenThe aims of this study were to clone the cDNA of Der f 14 corresponding to M-177 and to elucidate the allergenic capacities of the Der f 14-N.
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Making visible the invisible: Aboriginal forensic mental healthThe health of Aboriginal and Torres Strait Islander people in Australia is crucial to address due to the burden of disease and injury in aboriginal population.
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Associations between school absence and academic achievement: Do socioeconomics matter?School attendance should therefore be a priority for all schools, and not just those with high rates of absence or low average achievement.
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A novel technique of serial biopsy in mouse brain tumour modelsHere we describe a method by which serial biopsy can be used to validate response to dacomitinib treatment in vivo using a mouse glioblastoma model
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Sub-erythemal ultraviolet radiation reduces metabolic dysfunction in already overweight miceExposure to sunlight may limit cardiometabolic risk.
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Development of an International Database for a Rare Genetic Disorder: The MECP2 Duplication Database (MDBase)The natural history of MECP2 duplication syndrome (MDS), a rare X-linked neurodevelopmental disorder with an estimated birth prevalence of 1/150,000 live births, is poorly understood due to a lack of clinical data collected for research. Such information is critical to the understanding of disease progression, therapeutic endpoints and outcome measures for clinical trials, as well as the development of therapies and orphan products.
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The Lived Experience of Parents’ Receiving the Diagnosis of CDKL5 Deficiency Disorder for Their ChildCDKL5 deficiency disorder (CDD), a severe developmental and epileptic encephalopathy, is being diagnosed earlier with improved access to genetic testing, but this may also have unanticipated impacts on parents’ experience receiving the diagnosis. This study explores the lived experience of parents receiving a diagnosis of CDD for their child using mixed methods.
Research
Prevalence of electronic device use before bed among Australian children and adolescents: a cross-sectional population level studyTo understand the prevalence of children and adolescents’ electronic device use (EDU) in the hour before bed and identify sociodemographic groups that are at increased risk of problematic use.