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Research

Challenges to curing primary brain tumours

The seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment in brain tumours

Research

Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Clinical Review

Clinical presentations and genetic variations in Cyclin-dependent kinase-like 5 deficiency disorder based on a systematic literature review and experience

Research

The epidemiological transition in Papua New Guinea: new evidence from verbal autopsy studies

Our results indicate immediate priorities for health service planning and for strengthening of vital registration systems

Research

Selection of appropriate spirometry reference values in Aboriginal Australians

The Global Lung Function ‘Caucasian’ and ‘Other’ spirometry equations do not match healthy Aboriginal FEV1 and FVC data

Research

Vitamin D metabolites are lower with active Crohn’s disease and spontaneously recover with development of remission

We aimed to characterise vitamin D metabolism in a cohort of patients with active and inactive Crohn’s disease

Research

Folate Status and Neural Tube Defects in Aboriginal Australians: The Success of Mandatory Fortification in Reducing a Health Disparity

Mandatory flour fortification with folic acid in 2009, led to further reductions in overall neural tube defects

Research

Exposure to bile leads to the emergence of adaptive signaling variants in the opportunistic pathogen pseudomonas aeruginosa

Adaptive variants of P. aeruginosa that arise following long term bile exposure enables the emergence of ecologically competitive sub-populations

Research

Potential use of Western Australia’s mandatory Midwives Notification System for routinely monitoring antenatal vaccine coverage

We observed low sensitivity and specificity of antenatal vaccination data in the Midwives Notification System

Research

Lessons learned from a hospital-wide review of blood stream infections for paediatric central line-associated blood stream infection prevention

Health care-associated bacteraemia has a significant impact on child health, exceeding the number of community-acquired bacteraemia at our hospital

Research

Invasive fungal infections in children with acute lymphoblastic leukaemia: Results from four Australian centres, 2003-2013

Invasive fungal infections are more common in children with high-risk acute lymphoblastic leukaemia and in relapsed disease