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Effective targeting of the P53-MDM2 axis in preclinical models of infant MLL-rearranged acute lymphoblastic leukemia.This study describes the development and molecular characterization of a panel of patient-derived infant leukemia oncogene xenografts and their sensitivity...
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Breastfeeding and nutrition to 2 years of age and risk of childhood acute lymphoblastic leukemia and brain tumorsAcute lymphoblastic leukemia and childhood brain tumors are 2 of the most common forms of childhood cancer, but little is known of their etiology.
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HPV.edu study protocol: A cluster randomised controlled evaluation of education, decisional support and logistical strategies...The National Human Papillomavirus (HPV) Vaccination Program in Australia commenced in 2007 for females and in 2013 for males, using the quadrivalent HPV...
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T cells recognizing a 11mer influenza peptide complexed to H-2D b show promiscuity for peptide lengthT-cell repertoire is selected according to self peptide-MHC (major histocompatibility complex) complexes in the thymus.
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ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure.Two important risk factors for this disease are a positive family history and elevated intraocular pressure (IOP), which is also highly heritable.
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Cancer and mental illness: Key issues in mental healthOver many years, it has been shown that cancer represents a significant proportion of excess mortality for people with mental illness.
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The valuing of upstream approaches across the lifecourse. Fact Sheet 2 for the Aboriginal and Torres Strait Islander Suicide Prevention Evaluation ProjectThis factsheet highlights the need for a greater understanding of the importance of constructive & preventive ‘upstream’ approaches & sustained investment in...
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Evaluation in health promotion: Thoughts from inside a human research ethics committeeHealth promotion research, quality improvement and evaluation are all activities that raise ethical issues.
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A systematic review: Identifying the prevalence rates of psychiatric disorder in Australia's Indigenous populationsA systematic review: Identifying the prevalence rates of psychiatric disorder in Australia's Indigenous populations.
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Ultraviolet radiation suppresses obesity and symptoms of metabolic syndrome independently of vitamin DUVR or sunlight exposure may be an effective means of suppressing the development of obesity and MetS, through mechanisms that are independent of vitamin D