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Research that maps and tracks.
Research
Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8+ T cell immunity against melanomaA range of microbiota species correlate with improved cancer outcomes in patients and confer protection in pre-clinical mouse models. Here, we examined how microbiota regulate CD8+ T cell immunity against melanoma. Spontaneous control of cutaneous melanoma in mice correlated with metabolic pathways required for microbial synthesis of short-chain fatty acids (SCFAs) shared between several microbiota species.
Research
Change in Diet Quality and Dietary Intake From Pregnancy to 1-Year Postpartum: A Longitudinal Analysis in Australian WomenThis longitudinal analysis in Australian women evaluated change in diet quality and food and nutrient intakes from the third trimester of pregnancy to 1-year postpartum with comparison to national nutrition recommendations. Associations between diet quality, sociodemographic and health characteristics were also investigated.
In close partnership with Aboriginal Elders and community members in Western Australia's south-west, we created ‘Kaal Tackles Eczema’, a children’s book to help Aboriginal families manage eczema. Our research showed a high prevalence and need for culturally relevant resources. The book uses Noongar language and art to educate and reduce infections, and is available online and in schools.
Research
AsthmaOne in eight children have asthma, a chronic disease of the airways in the lungs. It results in shortness of breath, chest tightness, wheezing and coughing.
The Ngulluk Koolunga Ngulluk Koort (Our Children, Our Heart) Project grew out of a bold vision to harness the wisdom of Aboriginal Elders to improve outcomes for Aboriginal children, producing a suite of Elder-led, culturally appropriate and empowering initiatives that are making a difference.
Two international trials led by The Kids Research Institute Australia’s Neonatal and Infection Immunity Team are tackling the urgent need for simple and safe interventions that can help prevent the adverse long-term effects of infections in extremely preterm babies.
CliniKids, the first stand-alone clinical service offered by The Kids Research Institute Australia, was launched in October 2019 and is already delivering benefits for families with children who are developing differently.
A powerful data tool developed by international child development researcher Professor Sally Brinkman and former research assistant Tom Brown could improve early childhood support for children around the world after being launched in Dubai this year.
Facilitate research interest & opportunities that involve Aboriginal families & communities and build the capacity and development of Institute researchers