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The Strep A & ARF Therapeutics research team are working to accelerate research and clinical trials to improve penicillin formulation and treatment methods, to end RHD.
Research
Undiagnosed Diseases Program (UDP) and Bringing the benefits of precision medicine to children in Western AustraliaWe have started a project utilising whole genome sequencing of undiagnosed children living in WA to provide a definitive diagnosis. A major challenge here is that the role and functions of the inter-genic regions of our genome (the remaining 98%) are relatively poorly understood.
Research
An unbiased exploration of the human regulatory landscapeWe are made up of hundreds of different cell types carrying out a diverse range of functions essential for organism survival. All the information required to specify the morphology, function and response to stimuli of these cells is encoded in identical copies of the genome. The process of gene regu
We’ve heard from families that trustworthy information about preterm-associated lung disease is difficult to find. In response, we’ve created resources to empower families with the knowledge they need to manage these challenges.
Research
Physiological and inflammatory responses in an anthropomorphically relevant model of acute diesel exhaust particle exposure are sex and dose-dependentDiesel exhaust particles (DEP) are an important contributor to suspended particulate matter (PM) in urban areas. While epidemiological evidence exists for a...
Research
Effect of the increase in "alcopops" tax on alcohol-related harms in young people: a controlled interrupted time seriesThe objective of this study was to measure alcohol-related harms to the health of young people presenting to emergency...
Research
Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east IndiaIL8RA and IL8RB, encoded by CXCR1 and CXCR2, are receptors for interleukin (IL)-8 and other CXC chemokines involved in chemotaxis and activation of...
Research
Air travel and the risks of hypoxia in childrenIn infants and children with chronic respiratory disease, hypoxia is a potential risk of aircraft travel.
Research
Do hypertensive diseases of pregnancy disrupt neurocognitive development in offspring?Do hypertensive diseases of pregnancy disrupt neurocognitive development in offspring?
Research
Meningiomas in children and adolescents: a meta-analysis of individual patient dataThe epidemiological, prognostic, and therapeutic features of child and adolescent meningioma are poorly defined...