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Nutrition in Early Life

The vision of the Nutrition in Early Life team is to work together with the community to produce quality research, for improving our knowledge of how a mother’s diet during pregnancy and breastfeeding can improve both her and her child’s health.

The Nutrition in Early Life team conducts research investigating nutritional strategies for improved maternal and child health, including clinical trials, mechanistic studies and translatable research activities.

Our research includes identifying nutritional and environmental factors which influence the developing human immune system, particularly factors which predispose to allergic diseases (eczema, food allergy, hay fever and asthma in early childhood), as well as intervention studies for the prevention of allergic disease in childhood.

Team Highlights

  1. We have recruited more than 2000 mothers and babies in a current NHMRC funded large-scale multi-centre (Adelaide, Perth, Melbourne and Sydney) food allergy prevention study – known as the PrEggNut Study. This study is aiming to determine whether the risk of developing a food allergy can be reduced by a maternal diet rich in eggs and peanuts during pregnancy and breastfeeding.
  2. In 2023, we have completed the 1-year-old child follow-up and commenced the 5-year-old child follow-up of the NHMRC funded allergy prevention study, which recruited 652 mothers and their babies – known as the SYMBA Study. This study is aiming to determine whether the risk of a child developing any allergic diseases (including eczema, food allergy, asthma and hay fever) can be reduced by a maternal diet supplemented with prebiotics (a type of fibre) during pregnancy and breastfeeding.

Team leader

Debbie Palmer
Debbie Palmer

BSc BND PhD

Head, Early Life & Life-Course Health Program; Team Lead, Nutrition in Early Life

Team members (6)

Anita Jorgensen

Anita Jorgensen

National PrEggNut Study Coordinator

Emma Prescott

Emma Prescott

SYMBA Study Coordinator

Summer Walker

Summer Walker

Research Assistant

Deborah Lawrence

Deborah Lawrence

Research Nurse

Michelle Thompson

Michelle Thompson

Research Assistant

Kelly Faulkner

Kelly Faulkner

Research Nurse

Nutrition in Early Life projects

Featured projects

The PrEggNut Study – Maternal diet rich in eggs and peanuts to reduce food allergies: a randomised controlled trial

The SYMBA Study - Promoting Gut Health (SYMBiosis) for Allergy prevention

Higher maternal bread and thiamine intakes are associated with increased infant allergic disease

A mother's diet during pregnancy may influence her infant's immune development. However, as potential interactions between components of our dietary intakes can make any nutritional analysis complex, here we took a multi-component dietary analysis approach.

Impaired calcium influx underlies skewed T helper cell differentiation in children with IgE-mediated food allergies

Reasons for Th2 skewing in IgE-mediated food allergies remains unclear. Clinical observations suggest impaired T cell activation may drive Th2 responses evidenced by increased atopic manifestations in liver transplant patients on tacrolimus (a calcineurin inhibitor). We aimed to assess differentiation potential, T cell activation and calcium influx of naïve CD4+ T cells in children with IgE-mediated food allergies. 

Urinary Ferritin as a Noninvasive Means of Assessing Iron Status in Young Children

Iron deficiency (ID) is the most common nutritional deficiency affecting young children. Serum ferritin concentration is the preferred biomarker for measuring iron status because it reflects iron stores; however, blood collection can be distressing for young children and can be logistically difficult. A noninvasive means to measure iron status would be attractive to either diagnose or screen for ID in young children.

Maternal serum unmetabolized folic acid concentration following multivitamin and mineral supplementation with or without folic acid after 12 weeks gestation: A randomized controlled trial

Pregnant women are advised to take folic acid (FA) supplements before conception and during the first trimester of pregnancy. Many women continue FA supplementation throughout pregnancy, and concerns have been raised about associations between excessive FA intake and adverse maternal and child health outcomes.

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